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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.
Segovia, Mercedes; Russo, Sofia; Jeldres, Mathias; Mahmoud, Yamil D; Perez, Valentina; Duhalde, Maite; Charnet, Pierre; Rousset, Matthieu; Victoria, Sabina; Veigas, Florencia; Louvet, Cédric; Vanhove, Bernard; Floto, R Andrés; Anegon, Ignacio; Cuturi, Maria Cristina; Girotti, M Romina; Rabinovich, Gabriel A; Hill, Marcelo.
Afiliación
  • Segovia M; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay; Immunobiology Department, Faculty of Medicine, University of the Republic, 11800 Montevideo, Uruguay.
  • Russo S; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay; Immunobiology Department, Faculty of Medicine, University of the Republic, 11800 Montevideo, Uruguay.
  • Jeldres M; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay.
  • Mahmoud YD; Laboratories of Immunopathology and Translational Immuno-Oncology, Institute of Biology and Experimental Medicine (IBYME), National Council of Scientific and Technical Investigations (CONICET), C1428 Buenos Aires, Argentina.
  • Perez V; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay; Immunobiology Department, Faculty of Medicine, University of the Republic, 11800 Montevideo, Uruguay.
  • Duhalde M; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay.
  • Charnet P; Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS ENSCM, Université de Montpellier, 34093 Montpellier, France.
  • Rousset M; Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS ENSCM, Université de Montpellier, 34093 Montpellier, France.
  • Victoria S; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay.
  • Veigas F; Laboratories of Immunopathology and Translational Immuno-Oncology, Institute of Biology and Experimental Medicine (IBYME), National Council of Scientific and Technical Investigations (CONICET), C1428 Buenos Aires, Argentina.
  • Louvet C; INSERM UMR 1064, Center for Research in Transplantation and Immunology, Université de Nantes, CHU Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), 44093 Nantes, France.
  • Vanhove B; INSERM UMR 1064, Center for Research in Transplantation and Immunology, Université de Nantes, CHU Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), 44093 Nantes, France; Xenothera, 44093 Nantes, France.
  • Floto RA; Molecular Immunity Unit, Department of Medicine, University of Cambridge, CB2 0QH Cambridge, UK.
  • Anegon I; INSERM UMR 1064, Center for Research in Transplantation and Immunology, Université de Nantes, CHU Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), 44093 Nantes, France.
  • Cuturi MC; INSERM UMR 1064, Center for Research in Transplantation and Immunology, Université de Nantes, CHU Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), 44093 Nantes, France. Electronic address: ccuturi@nantes.inserm.fr.
  • Girotti MR; Laboratories of Immunopathology and Translational Immuno-Oncology, Institute of Biology and Experimental Medicine (IBYME), National Council of Scientific and Technical Investigations (CONICET), C1428 Buenos Aires, Argentina.
  • Rabinovich GA; Laboratories of Immunopathology and Translational Immuno-Oncology, Institute of Biology and Experimental Medicine (IBYME), National Council of Scientific and Technical Investigations (CONICET), C1428 Buenos Aires, Argentina; Department of Biological Chemistry, School of Exact and Natural Sciences, U
  • Hill M; Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, 11400 Montevideo, Uruguay; Immunobiology Department, Faculty of Medicine, University of the Republic, 11800 Montevideo, Uruguay. Electronic address: mhill@pasteur.edu.uy.
Cancer Cell ; 35(5): 767-781.e6, 2019 05 13.
Article en En | MEDLINE | ID: mdl-31085177
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inflamasomas / Proteínas de la Membrana / Neoplasias / Antineoplásicos Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Uruguay
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inflamasomas / Proteínas de la Membrana / Neoplasias / Antineoplásicos Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Uruguay