Model extrapolation to a real-world dataset: evaluation of tacrolimus population pharmacokinetics and drug interaction in pediatric liver transplantation patients.

Wang, Dong-Dong; Chen, Xiao; Fu, Meng; Zheng, Qing-Shan; Xu, Hong; Li, Zhi-Ping

Wang, Dong-Dong; Chen, Xiao; Fu, Meng; Zheng, Qing-Shan; Xu, Hong; Li, Zhi-Ping.

Afiliación

Wang DD; Department of Pharmacy, Children's Hospital of Fudan University, Shanghai, China.
Chen X; Department of Pharmacy, Children's Hospital of Fudan University, Shanghai, China.
Fu M; Department of Pharmacy, Children's Hospital of Fudan University, Shanghai, China.
Zheng QS; Center for Drug of Clinical Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xu H; Department of Nephrology, Children's Hospital of Fudan University, Shanghai, China.
Li ZP; Department of Pharmacy, Children's Hospital of Fudan University, Shanghai, China.

Xenobiotica ; 50(4): 371-379, 2020 Apr.

Article en En | MEDLINE | ID: mdl-31192749

Asunto(s)

Inmunosupresores/farmacocinética; Trasplante de Hígado; Modelos Estadísticos; Tacrolimus/farmacocinética; Niño; Interacciones Farmacológicas; Femenino; Humanos; Masculino; Modelos Biológicos

Palabras clave

Model extrapolation; pediatric liver transplantation; population pharmacokinetics; real-world dataset; tacrolimus

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Modelos Estadísticos / Trasplante de Hígado / Tacrolimus / Inmunosupresores Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Xenobiotica Año: 2020 Tipo del documento: Article País de afiliación: China

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