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The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats.
Moriya, Yuu; Kogame, Akifumi; Tagawa, Yoshihiko; Morohashi, Akio; Kondo, Takahiro; Asahi, Satoru; Benet, Leslie Z.
Afiliación
  • Moriya Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
  • Kogame A; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
  • Tagawa Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
  • Morohashi A; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
  • Kondo T; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
  • Asahi S; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
  • Benet LZ; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan (Y.M., A.K., Y.T., A.M., S.A.); Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Osaka, Japan (T.K.); and Univer
Drug Metab Dispos ; 47(9): 1004-1012, 2019 09.
Article en En | MEDLINE | ID: mdl-31201213
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tejido Subcutáneo / Kisspeptinas / Antineoplásicos Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tejido Subcutáneo / Kisspeptinas / Antineoplásicos Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article