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Differentiation of Deprotonated Acyl-, N-, and O-Glucuronide Drug Metabolites by Using Tandem Mass Spectrometry Based on Gas-Phase Ion-Molecule Reactions Followed by Collision-Activated Dissociation.
Niyonsaba, Edouard; Easton, McKay W; Feng, Erlu; Yu, Zaikuan; Zhang, Zhoupeng; Sheng, Huaming; Kong, John; Easterling, Leah F; Milton, Jacob; Chobanian, Harry R; Deprez, Nicholas R; Cancilla, Mark T; Kilaz, Gozdem; Kenttämaa, Hilkka I.
Afiliación
  • Niyonsaba E; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
  • Easton MW; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
  • Feng E; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
  • Yu Z; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
  • Zhang Z; Department of Pharmacokinetics, Pharmacodynamics, & Drug Metabolism , Merck & Co., Inc. , West Point , Pennsylvania 19486 , United States.
  • Sheng H; Analytical Research & Development , Merck & Co., Inc. , Rahway , New Jersey 07065 , United States.
  • Kong J; Analytical Research & Development , Merck & Co., Inc. , Rahway , New Jersey 07065 , United States.
  • Easterling LF; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
  • Milton J; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
  • Chobanian HR; Department of Pharmacokinetics, Pharmacodynamics, & Drug Metabolism , Merck & Co., Inc. , West Point , Pennsylvania 19486 , United States.
  • Deprez NR; Process Chemistry , Merck & Co., Inc. , Rahway , New Jersey 07065 , United States.
  • Cancilla MT; Department of Pharmacokinetics, Pharmacodynamics, & Drug Metabolism , Merck & Co., Inc. , West Point , Pennsylvania 19486 , United States.
  • Kilaz G; Purdue University , School of Engineering Technology , West Lafayette , Indiana 47907 , United States.
  • Kenttämaa HI; Department of Chemistry , Purdue University , West Lafayette , Indiana 47907 , United States.
Anal Chem ; 91(17): 11388-11396, 2019 09 03.
Article en En | MEDLINE | ID: mdl-31381321
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glucurónidos / Espectrometría de Masas en Tándem Idioma: En Revista: Anal Chem Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glucurónidos / Espectrometría de Masas en Tándem Idioma: En Revista: Anal Chem Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos