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Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.
Park, Sangeun; Park, Sei-Kyoung; Watanabe, Naruaki; Hashimoto, Tadafumi; Iwatsubo, Takeshi; Shelkovnikova, Tatyana A; Liebman, Susan W.
Afiliación
  • Park S; Department of Pharmacology, University of Nevada, Reno, Untied States of America.
  • Park SK; Department of Pharmacology, University of Nevada, Reno, Untied States of America.
  • Watanabe N; Department of Neuropathology, University of Tokyo, Tokyo, Japan.
  • Hashimoto T; Department of Neuropathology, University of Tokyo, Tokyo, Japan.
  • Iwatsubo T; Department of Neuropathology, University of Tokyo, Tokyo, Japan.
  • Shelkovnikova TA; Medicines Discovery Institute, Cardiff University, Cardiff, United Kingdom.
  • Liebman SW; Department of Pharmacology, University of Nevada, Reno, Untied States of America.
PLoS Genet ; 15(8): e1008308, 2019 08.
Article en En | MEDLINE | ID: mdl-31390360
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Transactivadores / Proteínas de Saccharomyces cerevisiae / Proteínas de Drosophila / Ataxina-2 / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Transactivadores / Proteínas de Saccharomyces cerevisiae / Proteínas de Drosophila / Ataxina-2 / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article