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Identification of drug-specific public TCR driving severe cutaneous adverse reactions.
Pan, Ren-You; Chu, Mu-Tzu; Wang, Chuang-Wei; Lee, Yun-Shien; Lemonnier, Francois; Michels, Aaron W; Schutte, Ryan; Ostrov, David A; Chen, Chun-Bing; Phillips, Elizabeth Jane; Mallal, Simon Alexander; Mockenhaupt, Maja; Bellón, Teresa; Tassaneeyakul, Wichittra; White, Katie D; Roujeau, Jean-Claude; Chung, Wen-Hung; Hung, Shuen-Iu.
Afiliación
  • Pan RY; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei, Keelung, Taoyuan, 333, Taiwan.
  • Chu MT; Cancer Vaccine and Immune Cell Therapy Core Laboratory, Chang Gung Immunology Consortium, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.
  • Wang CW; Institute of Pharmacology, National Yang-Ming University, Taipei, 112, Taiwan.
  • Lee YS; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei, Keelung, Taoyuan, 333, Taiwan.
  • Lemonnier F; Cancer Vaccine and Immune Cell Therapy Core Laboratory, Chang Gung Immunology Consortium, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.
  • Michels AW; Department of Biotechnology, Ming Chuan University, Taoyuan, 333, Taiwan.
  • Schutte R; INSERM U1016, Institut Cochin, Equipe Immunologie du Diabète, Hôpital Saint-Vincent-de-Paul, 75674, Paris, Cedex 14, France.
  • Ostrov DA; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, CO, 80204, USA.
  • Chen CB; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, 32611, USA.
  • Phillips EJ; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, 32611, USA.
  • Mallal SA; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Linkou, Taipei, Keelung, Taoyuan, 333, Taiwan.
  • Mockenhaupt M; Cancer Vaccine and Immune Cell Therapy Core Laboratory, Chang Gung Immunology Consortium, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.
  • Bellón T; College of Medicine, Chang Gung University, Taoyuan, 333, Taiwan.
  • Tassaneeyakul W; Departments of Medicine and Pathology, Microbiology and Immunology, School of Medicine, Vanderbilt University, Nashville, TN, 37235, USA.
  • White KD; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, 6150, WA, Australia.
  • Roujeau JC; Departments of Medicine and Pathology, Microbiology and Immunology, School of Medicine, Vanderbilt University, Nashville, TN, 37235, USA.
  • Chung WH; Institute for Immunology and Infectious Diseases, Murdoch University, Perth, 6150, WA, Australia.
  • Hung SI; Dokumentationszentrum schwerer Hautreaktionen (dZh), Department of Dermatology, Medical Center and Medical Faculty, University of Freiburg, Freiburg, 79085, Germany.
Nat Commun ; 10(1): 3569, 2019 08 08.
Article en En | MEDLINE | ID: mdl-31395875
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carbamazepina / Linfocitos T Citotóxicos / Síndrome de Stevens-Johnson / Receptores de Antígenos de Linfocitos T alfa-beta / Complejo Receptor-CD3 del Antígeno de Linfocito T Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Taiwán
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carbamazepina / Linfocitos T Citotóxicos / Síndrome de Stevens-Johnson / Receptores de Antígenos de Linfocitos T alfa-beta / Complejo Receptor-CD3 del Antígeno de Linfocito T Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Taiwán