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The role of kisspeptin system in cancer biology.
Stathaki, Martha; Stamatiou, Maria Evanthia; Magioris, George; Simantiris, Spyridon; Syrigos, Nikolaos; Dourakis, Spyridon; Koutsilieris, Michael; Armakolas, Athanasios.
Afiliación
  • Stathaki M; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece.
  • Stamatiou ME; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece.
  • Magioris G; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece.
  • Simantiris S; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece.
  • Syrigos N; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece.
  • Dourakis S; 2nd Academic Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens School of Medicine Hippokration General Hospital Athens Greece, Greece.
  • Koutsilieris M; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece.
  • Armakolas A; Physiology Laboratory, Athens Medical School, National and Kapodestrian University of Athens, Greece. Electronic address: aarmakol@med.uoa.gr.
Crit Rev Oncol Hematol ; 142: 130-140, 2019 Oct.
Article en En | MEDLINE | ID: mdl-31401420
ABSTRACT
Kisspeptins are a family of neuropeptides that are known to be critical in puberty initiation and ovulation. Apart from that kisspeptin derived peptides (KPs) are also known for their antimetastatic activities in several malignancies. Herein we report recent evidence of the role of kisspeptins in cancer biology and we examine the prospective of targeting the kisspeptin pathways leading to a better prognosis in patients with malignant diseases.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Kisspeptinas / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Crit Rev Oncol Hematol Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Grecia
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Kisspeptinas / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Crit Rev Oncol Hematol Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Grecia