Inhibition of Pancreatic &#945;-amylase by Resveratrol Derivatives: Biological Activity and Molecular Modelling Evidence for Cooperativity between Viniferin Enantiomers.

Mattio, Luce M; Marengo, Mauro; Parravicini, Chiara; Eberini, Ivano; Dallavalle, Sabrina; Bonomi, Francesco; Iametti, Stefania; Pinto, Andrea

Inhibition of Pancreatic α-amylase by Resveratrol Derivatives: Biological Activity and Molecular Modelling Evidence for Cooperativity between Viniferin Enantiomers.

Mattio, Luce M; Marengo, Mauro; Parravicini, Chiara; Eberini, Ivano; Dallavalle, Sabrina; Bonomi, Francesco; Iametti, Stefania; Pinto, Andrea.

Afiliación

Mattio LM; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milano, Italy.
Marengo M; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milano, Italy.
Parravicini C; Department of Pharmacological and Biomolecular Sciences (DiSFeB) & cDSRC, University of Milan, Via Balzaretti 9, 20133 Milano, Italy.
Eberini I; Department of Pharmacological and Biomolecular Sciences (DiSFeB) & cDSRC, University of Milan, Via Balzaretti 9, 20133 Milano, Italy.
Dallavalle S; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milano, Italy.
Bonomi F; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milano, Italy.
Iametti S; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milano, Italy.
Pinto A; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milano, Italy. andrea.pinto@unimi.it.

Molecules ; 24(18)2019 Sep 05.

Article en En | MEDLINE | ID: mdl-31491840

Asunto(s)

Inhibidores Enzimáticos/química; Inhibidores Enzimáticos/farmacología; alfa-Amilasas Pancreáticas/antagonistas & inhibidores; Resveratrol/química; Resveratrol/farmacología; Sitios de Unión; Conformación Molecular; Simulación del Acoplamiento Molecular; Simulación de Dinámica Molecular; Estructura Molecular; Unión Proteica; Relación Estructura-Actividad Cuantitativa; Resveratrol/análogos & derivados

Palabras clave

enzyme inhibition; food bioactives synergism; molecular docking; pancreatic alpha-amylase; resveratrol; stilbenoids

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Alfa-Amilasas Pancreáticas / Resveratrol Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Italia

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google