The long noncoding RNA <i>NEAT1_1</i> is seemingly dispensable for normal tissue homeostasis and cancer cell growth.

Adriaens, Carmen; Rambow, Florian; Bervoets, Greet; Silla, Toomas; Mito, Mari; Chiba, Tomoki; Asahara, Hiroshi; Hirose, Tetsuro; Nakagawa, Shinichi; Jensen, Torben Heick; Marine, Jean-Christophe

The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth.

Adriaens, Carmen; Rambow, Florian; Bervoets, Greet; Silla, Toomas; Mito, Mari; Chiba, Tomoki; Asahara, Hiroshi; Hirose, Tetsuro; Nakagawa, Shinichi; Jensen, Torben Heick; Marine, Jean-Christophe.

Afiliación

Adriaens C; Laboratory for Molecular Cancer Biology, Center for Cancer Biology, VIB, 3000 Leuven, Belgium.
Rambow F; Laboratory for Molecular Cancer Biology, Oncology Department, KU Leuven, 3000 Leuven, Belgium.
Bervoets G; Laboratory for Molecular Cancer Biology, Center for Cancer Biology, VIB, 3000 Leuven, Belgium.
Silla T; Laboratory for Molecular Cancer Biology, Oncology Department, KU Leuven, 3000 Leuven, Belgium.
Mito M; Laboratory for Molecular Cancer Biology, Center for Cancer Biology, VIB, 3000 Leuven, Belgium.
Chiba T; Laboratory for Molecular Cancer Biology, Oncology Department, KU Leuven, 3000 Leuven, Belgium.
Asahara H; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.
Hirose T; RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, 351-0198 Saitama, Japan.
Nakagawa S; Department of Systems BioMedicine, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.
Jensen TH; Department of Systems BioMedicine, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.
Marine JC; Institute for Genetic Medicine, Hokkaido University, 060-0808 Sapporo, Japan.

RNA ; 25(12): 1681-1695, 2019 12.

Article en En | MEDLINE | ID: mdl-31551298

Asunto(s)

Regulación Neoplásica de la Expresión Génica; Neoplasias/genética; ARN Largo no Codificante/genética; Empalme Alternativo; Animales; Ciclo Celular/efectos de los fármacos; Línea Celular; Proliferación Celular; Exosomas/metabolismo; Técnicas de Inactivación de Genes; Homeostasis; Humanos; Hibridación Fluorescente in Situ; Ratones; Neoplasias/metabolismo; Neoplasias/patología; Estabilidad del ARN; Estrés Fisiológico/genética; Transcriptoma

Palabras clave

NEAT1 isoforms; RNA exosome; cell cycle; lncRNA; mouse genetics; paraspeckles

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / ARN Largo no Codificante / Neoplasias Límite: Animals / Humans Idioma: En Revista: RNA Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Bélgica

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google