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A First-in-Human Trial of GLS4, a Novel Inhibitor of Hepatitis B Virus Capsid Assembly, following Single- and Multiple-Ascending-Oral-Dose Studies with or without Ritonavir in Healthy Adult Volunteers.
Zhao, Nan; Jia, Bo; Zhao, Hong; Xu, Junyu; Sheng, Xiaoyan; Luo, Lin; Huang, Zhangma; Wang, Xingan; Ren, Qingyun; Zhang, Yingjun; Zhao, Xia; Cui, Yimin.
Afiliación
  • Zhao N; Department of Pharmacy, Peking University First Hospital, Beijing, China.
  • Jia B; Department of Pharmacy, Peking University First Hospital, Beijing, China.
  • Zhao H; Department of Infectious Diseases, Center for Liver Disease, Peking University First Hospital, Beijing, China.
  • Xu J; Department of Pharmacy, Peking University First Hospital, Beijing, China.
  • Sheng X; Department of Pharmacy, Peking University First Hospital, Beijing, China.
  • Luo L; The State Key Laboratory of Anti-Infective Drug Development, HEC R&D Center, Sunshine Lake Pharma Co., Ltd., Dongguan, China.
  • Huang Z; The State Key Laboratory of Anti-Infective Drug Development, HEC R&D Center, Sunshine Lake Pharma Co., Ltd., Dongguan, China.
  • Wang X; The State Key Laboratory of Anti-Infective Drug Development, HEC R&D Center, Sunshine Lake Pharma Co., Ltd., Dongguan, China.
  • Ren Q; The State Key Laboratory of Anti-Infective Drug Development, HEC R&D Center, Sunshine Lake Pharma Co., Ltd., Dongguan, China.
  • Zhang Y; The State Key Laboratory of Anti-Infective Drug Development, HEC R&D Center, Sunshine Lake Pharma Co., Ltd., Dongguan, China.
  • Zhao X; Department of Pharmacy, Peking University First Hospital, Beijing, China zxyjk@126.com cui.pharm@pkufh.com.
  • Cui Y; Department of Pharmacy, Peking University First Hospital, Beijing, China zxyjk@126.com cui.pharm@pkufh.com.
Article en En | MEDLINE | ID: mdl-31636065

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / Cápside / Ritonavir Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Antimicrob Agents Chemother Año: 2019 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / Cápside / Ritonavir Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Antimicrob Agents Chemother Año: 2019 Tipo del documento: Article País de afiliación: China