Macrophages-derived p38&#945; promotes the experimental severe acute pancreatitis by regulating inflammation and autophagy.

Fan, Hui-Ning; Chen, Wei; Fan, Li-Na; Wu, Jing-Tong; Zhu, Jin-Shui; Zhang, Jing

Macrophages-derived p38α promotes the experimental severe acute pancreatitis by regulating inflammation and autophagy.

Fan, Hui-Ning; Chen, Wei; Fan, Li-Na; Wu, Jing-Tong; Zhu, Jin-Shui; Zhang, Jing.

Afiliación

Fan HN; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Chen W; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Fan LN; Department of Gastroenterology, Zhongshan Hospital, Xiamen University, Xiamen 361004, China.
Wu JT; Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310000, China.
Zhu JS; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. Electronic address: zhujs1803@163.com.
Zhang J; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. Electronic address: jing5522724@163.com.

Int Immunopharmacol ; 77: 105940, 2019 Dec.

Article en En | MEDLINE | ID: mdl-31655340

Asunto(s)

Autofagia/fisiología; Inflamación/metabolismo; Macrófagos/metabolismo; Pancreatitis/metabolismo; Pancreatitis/patología; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo; Enfermedad Aguda; Animales; Caspasa 1/metabolismo; Citocinas/metabolismo; Modelos Animales de Enfermedad; Imidazoles/farmacología; Macrófagos/efectos de los fármacos; Masculino; Ratones; Ratones Endogámicos C57BL; Proteínas Asociadas a Microtúbulos/metabolismo; Páncreas/metabolismo; Piridinas/farmacología; Transducción de Señal/fisiología

Palabras clave

Acute pancreatitis; Autophagy; Inflammation; Macrophages; P38α; ULK1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pancreatitis / Autofagia / Proteínas Quinasas p38 Activadas por Mitógenos / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China

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