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Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.
Zeng, Hao; Castillo-Cabrera, Johnny; Manser, Mika; Lu, Bo; Yang, Zinger; Strande, Vaik; Begue, Damien; Zamponi, Raffaella; Qiu, Shumei; Sigoillot, Frederic; Wang, Qiong; Lindeman, Alicia; Reece-Hoyes, John S; Russ, Carsten; Bonenfant, Debora; Jiang, Xiaomo; Wang, Youzhen; Cong, Feng.
Afiliación
  • Zeng H; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Castillo-Cabrera J; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Manser M; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Lu B; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Yang Z; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Strande V; Analytical Sciences and Imaging, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Begue D; Analytical Sciences and Imaging, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Zamponi R; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Qiu S; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Sigoillot F; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Wang Q; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Lindeman A; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Reece-Hoyes JS; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Russ C; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Bonenfant D; Analytical Sciences and Imaging, Novartis Institutes for Biomedical Research, Basel, Switzerland.
  • Jiang X; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Wang Y; Oncology Disease Area, Novartis Institutes for Biomedical Research, Cambridge, United States.
  • Cong F; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research, Cambridge, United States.
Elife ; 82019 11 19.
Article en En | MEDLINE | ID: mdl-31741433
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Sistemas CRISPR-Cas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Female / Humans Idioma: En Revista: Elife Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Sistemas CRISPR-Cas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Female / Humans Idioma: En Revista: Elife Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos