Three-month mortality in permanently bedridden medical non-oncologic patients. The BECLAP study (permanently BEdridden, creatinine CLearance, albumin, previous hospital admissions study).
Eur J Intern Med
; 72: 60-66, 2020 02.
Article
en En
| MEDLINE
| ID: mdl-31757579
ABSTRACT
OBJECTIVE:
To predict the 3-months mortality in permanently bedridden medical non-oncologic inpatients. PATIENTS ANDMETHODS:
2788 consecutive patients admitted in 5 Italian Internal Medicine units from January 2016 through January 2017 were prospectively screened; 644 oncologic patients were excluded; 2144 non-oncologic patients (1021 female) were followed-up for mortality for 6 months. Main outcome was 3-months mortality in permanently bedridden inpatients with at least 2 of creatinine clearance <35â¯ml/min; albuminâ¯<â¯2.5â¯g/dl; at least 2 hospital admissions in the previous 6 months. Advanced dementia and dysphagia were also recorded.RESULTS:
Mean age of the 2144 patients was 73.9 (SD, 14.9) years; 374 (17%) were permanently bedridden, 435 (20%) had a creatinine clearance <35â¯ml/min, 217 (10%) albumin <2,5â¯g/dl, 112 (5%) at least 2 hospital admissions in the previous 6 months. Seventy-seven (4%) patients were permanently bedridden with at least 2 of the above mentioned items, and 48 of them died within 3 months (62%) (pâ¯<â¯0.001;95% CI 51-73%). Regression coefficients of the variables associated with 3-months mortality in multivariate analysis in 998 patients of unit 1 (training cohort) were used to create a simple score, which was validated in the 1146 patients of the other units (validation cohort) and performed well in predicting the 3-months mortality (https//www.ejcrim.com/beclap/).CONCLUSIONS:
Approximately two out of three non-oncologic medical patients permanently bedridden having 2 of the abovementioned items are dead 3 months after index admission; a simple score including bedridden status, creatinine clearance, albumin, dysphagia, age and sex may help discuss management priorities.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Albúminas
/
Hospitalización
Tipo de estudio:
Prognostic_studies
Límite:
Aged
/
Female
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur J Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2020
Tipo del documento:
Article