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Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions.
Halachev, Mihail; Meynert, Alison; Taylor, Martin S; Vitart, Veronique; Kerr, Shona M; Klaric, Lucija; Aitman, Timothy J; Haley, Chris S; Prendergast, James G; Pugh, Carys; Hume, David A; Harris, Sarah E; Liewald, David C; Deary, Ian J; Semple, Colin A; Wilson, James F.
Afiliación
  • Halachev M; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Meynert A; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Taylor MS; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Vitart V; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Kerr SM; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Klaric L; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Aitman TJ; Centre for Genomic and Experimental Medicine, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Haley CS; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
  • Prendergast JG; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
  • Pugh C; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
  • Hume DA; Centre for Clinical Brain Sciences, Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.
  • Harris SE; Mater Research Institute, University of Queensland, Woolloongabba, Australia.
  • Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, George Square, Edinburgh, United Kingdom.
  • Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, George Square, Edinburgh, United Kingdom.
  • Semple CA; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, George Square, Edinburgh, United Kingdom.
  • Wilson JF; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Crewe Road, Edinburgh, United Kingdom.
PLoS Genet ; 15(11): e1008480, 2019 11.
Article en En | MEDLINE | ID: mdl-31765389
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Secuencias Reguladoras de Ácidos Nucleicos / Demografía / Genética de Población Tipo de estudio: Risk_factors_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Secuencias Reguladoras de Ácidos Nucleicos / Demografía / Genética de Población Tipo de estudio: Risk_factors_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido