Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O6-Methylguanine Methyltransferase, MGMT.

Thongararm, Pennapa; Fedeles, Bogdan I; Khumsubdee, Sakunchai; Armijo, Amanda L; Kim, Lina; Thiantanawat, Apinya; Promvijit, Jeerawan; Navasumrit, Panida; Ruchirawat, Mathuros; Croy, Robert G; Essigmann, John M

Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O⁶-Methylguanine Methyltransferase, MGMT.

Thongararm, Pennapa; Fedeles, Bogdan I; Khumsubdee, Sakunchai; Armijo, Amanda L; Kim, Lina; Thiantanawat, Apinya; Promvijit, Jeerawan; Navasumrit, Panida; Ruchirawat, Mathuros; Croy, Robert G; Essigmann, John M.

Afiliación

Thongararm P; Departments of Biological Engineering and Chemistry, and Center for Environmental Health Sciences , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Fedeles BI; Chulabhorn Research Institute , Bangkok 10210 , Thailand.
Khumsubdee S; Departments of Biological Engineering and Chemistry, and Center for Environmental Health Sciences , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Armijo AL; Departments of Biological Engineering and Chemistry, and Center for Environmental Health Sciences , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Kim L; Chulabhorn Research Institute , Bangkok 10210 , Thailand.
Thiantanawat A; Departments of Biological Engineering and Chemistry, and Center for Environmental Health Sciences , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Promvijit J; Departments of Biological Engineering and Chemistry, and Center for Environmental Health Sciences , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Navasumrit P; Chulabhorn Research Institute , Bangkok 10210 , Thailand.
Ruchirawat M; Chulabhorn Research Institute , Bangkok 10210 , Thailand.
Croy RG; Chulabhorn Research Institute , Bangkok 10210 , Thailand.
Essigmann JM; Chulabhorn Research Institute , Bangkok 10210 , Thailand.

Chem Res Toxicol ; 33(2): 625-633, 2020 02 17.

Article en En | MEDLINE | ID: mdl-31841318

Asunto(s)

Alquilantes/farmacología; Metilasas de Modificación del ADN/antagonistas & inhibidores; Enzimas Reparadoras del ADN/antagonistas & inhibidores; Inhibidores Enzimáticos/farmacología; Fibroblastos/efectos de los fármacos; Metilnitrosourea/farmacología; Mutagénesis/efectos de los fármacos; Proteínas Supresoras de Tumor/antagonistas & inhibidores; Alquilantes/química; Animales; Metilasas de Modificación del ADN/metabolismo; Enzimas Reparadoras del ADN/metabolismo; Inhibidores Enzimáticos/química; Fibroblastos/metabolismo; Metilnitrosourea/química; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; Proteínas Supresoras de Tumor/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Metilasas de Modificación del ADN / Mutagénesis / Proteínas Supresoras de Tumor / Enzimas Reparadoras del ADN / Alquilantes / Inhibidores Enzimáticos / Fibroblastos / Metilnitrosourea Tipo de estudio: Qualitative_research Límite: Animals Idioma: En Revista: Chem Res Toxicol Asunto de la revista: TOXICOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google