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Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation.
Moonira, Tabassum; Chachra, Shruti S; Ford, Brian E; Marin, Silvia; Alshawi, Ahmed; Adam-Primus, Natasha S; Arden, Catherine; Al-Oanzi, Ziad H; Foretz, Marc; Viollet, Benoit; Cascante, Marta; Agius, Loranne.
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  • Moonira T; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Chachra SS; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Ford BE; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Marin S; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, 08007 Barcelona, Spain; CIBEREHD and Metabolomics Node at INB-Bioinformatics Platform, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Alshawi A; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Adam-Primus NS; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Arden C; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Al-Oanzi ZH; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.
  • Foretz M; INSERM, U1016, Institut Cochin, Paris 75014, France; CNRS, UMR8104, Paris 75014, France; Université Paris Descartes, Sorbonne Paris Cité, Paris 75014, France.
  • Viollet B; INSERM, U1016, Institut Cochin, Paris 75014, France; CNRS, UMR8104, Paris 75014, France; Université Paris Descartes, Sorbonne Paris Cité, Paris 75014, France.
  • Cascante M; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, 08007 Barcelona, Spain; CIBEREHD and Metabolomics Node at INB-Bioinformatics Platform, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Agius L; Biosciences Institute, Newcastle University, Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom. Electronic address: loranne.agius@ncl.ac.uk.
J Biol Chem ; 295(10): 3330-3346, 2020 03 06.
Article en En | MEDLINE | ID: mdl-31974165
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glucosa-6-Fosfato / Glucosa / Glucólisis / Metformina Límite: Animals Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glucosa-6-Fosfato / Glucosa / Glucólisis / Metformina Límite: Animals Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido