Contribution of the Presenilins in the cell biology, structure and function of Î³-secretase.

Escamilla-Ayala, Abril; Wouters, Rosanne; Sannerud, Ragna; Annaert, Wim

Escamilla-Ayala, Abril; Wouters, Rosanne; Sannerud, Ragna; Annaert, Wim.

Afiliación

Escamilla-Ayala A; Laboratory for Membrane Trafficking, VIB-Center for Brain and Disease Research, Leuven, Belgium; Department of Neurosciences, KU Leuven, Leuven, Belgium.
Wouters R; Laboratory for Membrane Trafficking, VIB-Center for Brain and Disease Research, Leuven, Belgium; Department of Neurosciences, KU Leuven, Leuven, Belgium.
Sannerud R; Laboratory for Membrane Trafficking, VIB-Center for Brain and Disease Research, Leuven, Belgium; Department of Neurosciences, KU Leuven, Leuven, Belgium.
Annaert W; Laboratory for Membrane Trafficking, VIB-Center for Brain and Disease Research, Leuven, Belgium; Department of Neurosciences, KU Leuven, Leuven, Belgium. Electronic address: wim.annaert@kuleuven.vib.be.

Semin Cell Dev Biol ; 105: 12-26, 2020 09.

Article en En | MEDLINE | ID: mdl-32146031

Asunto(s)

Enfermedad de Alzheimer/genética; Secretasas de la Proteína Precursora del Amiloide/metabolismo; Biología Celular/normas; Presenilinas/metabolismo; Humanos

Palabras clave

APP; Alzheimer's disease; Amyloid beta; Assembly; Conformation; Endosomes; Familial AD; Gamma-secretase; Inhibitor; Interactor; Lysosomes; Presenilin 1; Presenilin 2; Structure; Subcellular localization; Transport Regulation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biología Celular / Secretasas de la Proteína Precursora del Amiloide / Presenilinas / Enfermedad de Alzheimer Límite: Humans Idioma: En Revista: Semin Cell Dev Biol Asunto de la revista: EMBRIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Bélgica

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