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Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Joshi, Sachindra Raj; Kitagawa, Atsushi; Jacob, Christina; Hashimoto, Ryota; Dhagia, Vidhi; Ramesh, Amrit; Zheng, Connie; Zhang, Hui; Jordan, Allan; Waddell, Ian; Leopold, Jane; Hu, Cheng-Jun; McMurtry, Ivan F; D'Alessandro, Angelo; Stenmark, Kurt R; Gupte, Sachin A.
Afiliación
  • Joshi SR; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • Kitagawa A; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • Jacob C; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • Hashimoto R; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • Dhagia V; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • Ramesh A; Department of Pharmacology, New York Medical College, Valhalla, New York.
  • Zheng C; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Zhang H; Division of Pediatric Critical Care Medicine, Cardiovascular Pulmonary Research and Developmental Lung Biology Laboratories, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Jordan A; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
  • Waddell I; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom.
  • Leopold J; Department of Medicine, Division of Cardiology, Brigham Women and Children's Hospital, Harvard School of Medicine, Boston, Massachusetts.
  • Hu CJ; Department of Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • McMurtry IF; Departments of Pharmacology and Internal Medicine and Center for Lung Biology, University of South Alabama, Mobile, Alabama.
  • D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Stenmark KR; Division of Pediatric Critical Care Medicine, Cardiovascular Pulmonary Research and Developmental Lung Biology Laboratories, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Gupte SA; Department of Pharmacology, New York Medical College, Valhalla, New York.
Am J Physiol Lung Cell Mol Physiol ; 318(4): L773-L786, 2020 04 01.
Article en En | MEDLINE | ID: mdl-32159369
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Metilación de ADN / Glucosafosfato Deshidrogenasa / Hipertensión Pulmonar / Hipoxia Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Asunto de la revista: BIOLOGIA MOLECULAR / FISIOLOGIA Año: 2020 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Metilación de ADN / Glucosafosfato Deshidrogenasa / Hipertensión Pulmonar / Hipoxia Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Asunto de la revista: BIOLOGIA MOLECULAR / FISIOLOGIA Año: 2020 Tipo del documento: Article