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Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies.
Leemans, Margaux; Galicia, Christian; Deyaert, Egon; Daems, Elise; Krause, Linda; Paesmans, Jone; Pardon, Els; Steyaert, Jan; Kortholt, Arjan; Sobott, Frank; Klostermeier, Dagmar; Versées, Wim.
Afiliación
  • Leemans M; VIB-VUB Center for Structural Biology, Pleinlaan 2, 1050 Brussels, Belgium.
  • Galicia C; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
  • Deyaert E; VIB-VUB Center for Structural Biology, Pleinlaan 2, 1050 Brussels, Belgium.
  • Daems E; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
  • Krause L; VIB-VUB Center for Structural Biology, Pleinlaan 2, 1050 Brussels, Belgium.
  • Paesmans J; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
  • Pardon E; Department of Chemistry, Biomolecular and Analytical Mass Spectrometry Group, University of Antwerp, Antwerp, Belgium.
  • Steyaert J; Department of Bioscience Engineering, Antwerp X-ray Analysis, Electrochemistry and Speciation Group, University of Antwerp, Antwerp, Belgium.
  • Kortholt A; University of Münster, Institute for Physical Chemistry, Corrensstrasse 30, D-48149 Münster, Germany.
  • Sobott F; VIB-VUB Center for Structural Biology, Pleinlaan 2, 1050 Brussels, Belgium.
  • Klostermeier D; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
  • Versées W; VIB-VUB Center for Structural Biology, Pleinlaan 2, 1050 Brussels, Belgium.
Biochem J ; 477(7): 1203-1218, 2020 04 17.
Article en En | MEDLINE | ID: mdl-32167135
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Proteínas ras / Chlorobi / Anticuerpos de Dominio Único / Proteína 2 Quinasa Serina-Treonina Rica en Repeticiones de Leucina / Dominios Proteicos / GTP Fosfohidrolasas Límite: Animals Idioma: En Revista: Biochem J Año: 2020 Tipo del documento: Article País de afiliación: Bélgica
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Proteínas ras / Chlorobi / Anticuerpos de Dominio Único / Proteína 2 Quinasa Serina-Treonina Rica en Repeticiones de Leucina / Dominios Proteicos / GTP Fosfohidrolasas Límite: Animals Idioma: En Revista: Biochem J Año: 2020 Tipo del documento: Article País de afiliación: Bélgica