Mitochondrial GSDMD Pores DAMPen Pyroptosis.

Barnett, Katherine C; Ting, Jenny P-Y

Barnett, Katherine C; Ting, Jenny P-Y.

Afiliación

Barnett KC; University of North Carolina, Chapel Hill, Chapel Hill, NC, USA.
Ting JP; University of North Carolina, Chapel Hill, Chapel Hill, NC, USA. Electronic address: jenny_ting@med.unc.edu.

Immunity ; 52(3): 424-426, 2020 03 17.

Article en En | MEDLINE | ID: mdl-32187511

ABSTRACT

ABSTRACT

Noncanoncial inflammasome activation by cytosolic lipopolysaccharide (LPS) causes pyroptotic cell death facilitated by gasdermin D (GSDMD) pore formation. In this issue of Immunity, Huang et al. describe how cytosolic LPS in endothelial cells does not cause cell death but restrains endothelial cell proliferation.

Asunto(s)

ADN Mitocondrial; Piroptosis; Proliferación Celular; Células Endoteliales; Proteínas de Neoplasias; Nucleotidiltransferasas

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN Mitocondrial / Piroptosis Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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