Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology.

ABSTRACT

Delay and noise are inevitable in complex systems that are common in biochemical networks. The system is often disturbed at various states irrespective of the size (small or large) of delay and noise. Therefore, it is of interest to describe the significance of delay and noise in stochastic Willamowski-Rossler chemical oscillator model using a delay stochastic (having random probability distribution) simulation algorithm. Oscillating dynamics moves to stable fixed point when delay at a fixed magnitude of noise drives the system from oscillating state to stochastic amplitude death state (complete cessation). However, the amplitude death state is induced to a revived oscillating state in stochastic system (which is far from equilibrium state) for noise with a fixed value of delay. Thus, significantly large and small noise induces the dynamics of the system to amplitude death state. Hence, we describe the interplay of delay and noise in stochastic systems for the proper and efficient functioning of the complex system that are frequent in biological networks.