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Serum albumin-binding VH Hs with variable pH sensitivities enable tailored half-life extension of biologics.
van Faassen, Henk; Ryan, Shannon; Henry, Kevin A; Raphael, Shalini; Yang, Qingling; Rossotti, Martin A; Brunette, Eric; Jiang, Susan; Haqqani, Arsalan S; Sulea, Traian; MacKenzie, C Roger; Tanha, Jamshid; Hussack, Greg.
Afiliación
  • van Faassen H; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Ryan S; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Henry KA; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Raphael S; Department of Biochemistry, Microbiology & Immunology, University of Ottawa, Ottawa, ON, Canada.
  • Yang Q; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Rossotti MA; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Brunette E; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Jiang S; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Haqqani AS; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Sulea T; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • MacKenzie CR; Human Health Therapeutics Research Centre, National Research Council Canada, Montréal, QC, Canada.
  • Tanha J; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
  • Hussack G; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, ON, Canada.
FASEB J ; 34(6): 8155-8171, 2020 06.
Article en En | MEDLINE | ID: mdl-32342547
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Productos Biológicos / Albúmina Sérica Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Productos Biológicos / Albúmina Sérica Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Canadá