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Drug-induced QT prolongation: Concordance of preclinical anesthetized canine model in relation to published clinical observations for ten CiPA drugs.
Koshman, Yevgeniya E; Wilsey, Amanda S; Bird, Brandan M; Endemann, Aimee L; Sadilek, Sabine; Treadway, Jessica; Martin, Ruth L; Polakowski, James S; Gintant, Gary A; Mittelstadt, Scott W.
Afiliación
  • Koshman YE; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America. Electronic address: yevgeniya.koshman@abbvie.com.
  • Wilsey AS; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Bird BM; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Endemann AL; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Sadilek S; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Treadway J; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Martin RL; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Polakowski JS; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Gintant GA; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
  • Mittelstadt SW; AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064, United States of America.
J Pharmacol Toxicol Methods ; 103: 106871, 2020.
Article en En | MEDLINE | ID: mdl-32360993
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Torsades de Pointes / Antiarrítmicos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: J Pharmacol Toxicol Methods Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de QT Prolongado / Torsades de Pointes / Antiarrítmicos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: J Pharmacol Toxicol Methods Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2020 Tipo del documento: Article