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The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell- and antibody-mediated rejection.
Loupy, Alexandre; Haas, Mark; Roufosse, Candice; Naesens, Maarten; Adam, Benjamin; Afrouzian, Marjan; Akalin, Enver; Alachkar, Nada; Bagnasco, Serena; Becker, Jan U; Cornell, Lynn D; Clahsen-van Groningen, Marian C; Demetris, Anthony J; Dragun, Duska; Duong van Huyen, Jean-Paul; Farris, Alton B; Fogo, Agnes B; Gibson, Ian W; Glotz, Denis; Gueguen, Juliette; Kikic, Zeljko; Kozakowski, Nicolas; Kraus, Edward; Lefaucheur, Carmen; Liapis, Helen; Mannon, Roslyn B; Montgomery, Robert A; Nankivell, Brian J; Nickeleit, Volker; Nickerson, Peter; Rabant, Marion; Racusen, Lorraine; Randhawa, Parmjeet; Robin, Blaise; Rosales, Ivy A; Sapir-Pichhadze, Ruth; Schinstock, Carrie A; Seron, Daniel; Singh, Harsharan K; Smith, Rex N; Stegall, Mark D; Zeevi, Adriana; Solez, Kim; Colvin, Robert B; Mengel, Michael.
Afiliación
  • Loupy A; Université de Paris, INSERM U970, University of Paris, Paris Translational Research Centre for Organ Transplantation, Paris and Necker Hospital, Assistance Publique - Hopitaux de Paris, Paris, France.
  • Haas M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.
  • Roufosse C; Department of Immunology and Inflammation, Imperial College London and North West London Pathology, London, UK.
  • Naesens M; Department of Microbiology and Immunology, University of Leuven, Leuven, Belgium.
  • Adam B; Department of Nephrology, University Hospitals Leuven, Leuven, Belgium.
  • Afrouzian M; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.
  • Akalin E; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
  • Alachkar N; Montefiore-Einstein Center for Transplantation, Montefiore Medical Center, Bronx, New York, USA.
  • Bagnasco S; Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Becker JU; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Cornell LD; Institute of Pathology, University Hospital of Cologne, Cologne, Germany.
  • Clahsen-van Groningen MC; Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
  • Demetris AJ; Department of Pathology, Erasmus MC, Rotterdam, the Netherlands.
  • Dragun D; Department of Pathology, The Thomas E Starzl Transplantation Institute, University of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Duong van Huyen JP; Department of Nephrology and Critical Care Medicine, Berlin Institute of Health, Charite Universitätsmedizin, Berlin, Germany.
  • Farris AB; Université de Paris, INSERM U970, University of Paris, Paris Translational Research Centre for Organ Transplantation, Paris and Necker Hospital, Assistance Publique - Hopitaux de Paris, Paris, France.
  • Fogo AB; Emory University, Atlanta, Georgia, USA.
  • Gibson IW; Departments of Pathology, Microbiology, and Immunology; Medicine and Pediatrics, Vanderbilt University, Nashville, Tennessee, USA.
  • Glotz D; Department of Pathology, University of Manitoba, Winnipeg, Canada.
  • Gueguen J; Paris Translational Research Center for Organ Transplantation, Department of Nephrology and Transplantation, Hopital Saint Louis, Université Paris VII, INSERM U 1160, Paris, France.
  • Kikic Z; Université de Paris, INSERM U970, University of Paris, Paris Translational Research Centre for Organ Transplantation, Paris and Necker Hospital, Assistance Publique - Hopitaux de Paris, Paris, France.
  • Kozakowski N; Departments of Medicine and Pathology, Medical University of Vienna, Vienna, Austria.
  • Kraus E; Departments of Medicine and Pathology, Medical University of Vienna, Vienna, Austria.
  • Lefaucheur C; Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Liapis H; Paris Translational Research Center for Organ Transplantation, Department of Nephrology and Transplantation, Hopital Saint Louis, Université Paris VII, INSERM U 1160, Paris, France.
  • Mannon RB; Department of Pathology & Immunology & Internal Medicine (Renal) Retired, Washington University School of Medicine, Saint Louis, Missouri, USA.
  • Montgomery RA; Division of Nephrology, Department of Medicine, University of Alabama School of Medicine, Birmingham, Alabama, USA.
  • Nankivell BJ; New York University Langone Medical Center, NYU Langone Transplant Institute, New York, New York, USA.
  • Nickeleit V; Department of Renal Medicine, Westmead Hospital, Sydney, Australia.
  • Nickerson P; Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina, Chapel Hill, North Carolina, USA.
  • Rabant M; Department of Internal Medicine and Immunology, University of Manitoba, Winnipeg, Canada.
  • Racusen L; Université de Paris, INSERM U970, University of Paris, Paris Translational Research Centre for Organ Transplantation, Paris and Necker Hospital, Assistance Publique - Hopitaux de Paris, Paris, France.
  • Randhawa P; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Robin B; Department of Pathology, The Thomas E Starzl Transplantation Institute, University of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Rosales IA; Université de Paris, INSERM U970, University of Paris, Paris Translational Research Centre for Organ Transplantation, Paris and Necker Hospital, Assistance Publique - Hopitaux de Paris, Paris, France.
  • Sapir-Pichhadze R; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Schinstock CA; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Canada.
  • Seron D; William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, Minnesota, USA.
  • Singh HK; Nephrology Department, Hospital Vall d'Hebron, Autonomous University of Barcelona, Barcelona, Spain.
  • Smith RN; Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina, Chapel Hill, North Carolina, USA.
  • Stegall MD; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Zeevi A; Departments of Surgery and Immunology, Mayo Clinic, Rochester, Minnesota, USA.
  • Solez K; Department of Pathology, The Thomas E Starzl Transplantation Institute, University of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Colvin RB; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.
  • Mengel M; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Am J Transplant ; 20(9): 2318-2331, 2020 09.
Article en En | MEDLINE | ID: mdl-32463180
ABSTRACT
The XV. Banff conference for allograft pathology was held in conjunction with the annual meeting of the American Society for Histocompatibility and Immunogenetics in Pittsburgh, PA (USA) and focused on refining recent updates to the classification, advances from the Banff working groups, and standardization of molecular diagnostics. This report on kidney transplant pathology details clarifications and refinements to the criteria for chronic active (CA) T cell-mediated rejection (TCMR), borderline, and antibody-mediated rejection (ABMR). The main focus of kidney sessions was on how to address biopsies meeting criteria for CA TCMR plus borderline or acute TCMR. Recent studies on the clinical impact of borderline infiltrates were also presented to clarify whether the threshold for interstitial inflammation in diagnosis of borderline should be i0 or i1. Sessions on ABMR focused on biopsies showing microvascular inflammation in the absence of C4d staining or detectable donor-specific antibodies; the potential value of molecular diagnostics in such cases and recommendations for use of the latter in the setting of solid organ transplantation are presented in the accompanying meeting report. Finally, several speakers discussed the capabilities of artificial intelligence and the potential for use of machine learning algorithms in diagnosis and personalized therapeutics in solid organ transplantation.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Riñón / Rechazo de Injerto Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Riñón / Rechazo de Injerto Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: Francia