miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.

Guan, Guo-Ying; Wei, Nan; Song, Tao; Zhao, Chao; Sun, Yang; Pan, Ru-Xin; Zhang, Lu-Lu; Xu, Ying-Ying; Dai, Ya-Mei; Han, Hui

Guan, Guo-Ying; Wei, Nan; Song, Tao; Zhao, Chao; Sun, Yang; Pan, Ru-Xin; Zhang, Lu-Lu; Xu, Ying-Ying; Dai, Ya-Mei; Han, Hui.

Afiliación

Guan GY; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wei N; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Song T; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhao C; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Sun Y; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Pan RX; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhang LL; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xu YY; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Dai YM; Physical Examination Center, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Han H; Department of Geriatrics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

J Cell Physiol ; 235(12): 10024-10036, 2020 12.

Article en En | MEDLINE | ID: mdl-32542696

Asunto(s)

Diabetes Mellitus/genética; Angiopatías Diabéticas/genética; Dipeptidil Peptidasa 4/genética; MicroARNs/genética; Animales; Diabetes Mellitus/patología; Diabetes Mellitus Experimental/complicaciones; Diabetes Mellitus Experimental/genética; Diabetes Mellitus Experimental/patología; Angiopatías Diabéticas/patología; Células Endoteliales/metabolismo; Células Endoteliales/patología; Transición Epitelial-Mesenquimal/genética; Humanos; Ratas

Palabras clave

DPP-4; EndMT; TGF-ß/Smad pathway; diabetic endothelial dysfunction; miR-448-3p

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Dipeptidil Peptidasa 4 / MicroARNs / Diabetes Mellitus / Angiopatías Diabéticas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cell Physiol Año: 2020 Tipo del documento: Article País de afiliación: China

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