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Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
Chen, Zhuoyao; Wasney, Gregory A; Picaud, Sarah; Filippakopoulos, Panagis; Vedadi, Masoud; D'Angiolella, Vincenzo; Bullock, Alex N.
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  • Chen Z; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Wasney GA; Structural Genomics Consortium, University of Toronto, MaRS Centre, South Tower, 101 College Street, Toronto, M5G 1L7, Canada.
  • Picaud S; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Filippakopoulos P; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Vedadi M; Structural Genomics Consortium, University of Toronto, MaRS Centre, South Tower, 101 College Street, Toronto, M5G 1L7, Canada.
  • D'Angiolella V; Department of Oncology, Cancer Research UK and Medical Research Council Institute for Radiation Oncology, University of Oxford, Oxford OX3 7DQ, UK.
  • Bullock AN; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
Open Biol ; 10(6): 200041, 2020 06.
Article en En | MEDLINE | ID: mdl-32574548
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Adaptadoras Transductoras de Señales / Proteínas Dishevelled / Mutación Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Open Biol Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Adaptadoras Transductoras de Señales / Proteínas Dishevelled / Mutación Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Open Biol Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido