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A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing.
Zhang, Wen-Wei; Karmakar, Subir; Gannavaram, Sreenivas; Dey, Ranadhir; Lypaczewski, Patrick; Ismail, Nevien; Siddiqui, Abid; Simonyan, Vahan; Oliveira, Fabiano; Coutinho-Abreu, Iliano V; DeSouza-Vieira, Thiago; Meneses, Claudio; Oristian, James; Serafim, Tiago D; Musa, Abu; Nakamura, Risa; Saljoughian, Noushin; Volpedo, Greta; Satoskar, Monika; Satoskar, Sanika; Dagur, Pradeep K; McCoy, J Philip; Kamhawi, Shaden; Valenzuela, Jesus G; Hamano, Shinjiro; Satoskar, Abhay R; Matlashewski, Greg; Nakhasi, Hira L.
Afiliación
  • Zhang WW; Department of Microbiology and Immunology, McGill University, Montreal, QC, H3A 2B4, Canada.
  • Karmakar S; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Gannavaram S; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Dey R; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Lypaczewski P; Department of Microbiology and Immunology, McGill University, Montreal, QC, H3A 2B4, Canada.
  • Ismail N; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Siddiqui A; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Simonyan V; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Oliveira F; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Coutinho-Abreu IV; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • DeSouza-Vieira T; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Meneses C; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Oristian J; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Serafim TD; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Musa A; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan and Nagasaki University Graduate School of Biomedical Sciences Doctoral Leadership Program, Nagasaki, Japan.
  • Nakamura R; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan and Nagasaki University Graduate School of Biomedical Sciences Doctoral Leadership Program, Nagasaki, Japan.
  • Saljoughian N; Department of Pathology and Microbiology, Ohio State University, Columbus, OH, 43210, USA.
  • Volpedo G; Department of Pathology and Microbiology, Ohio State University, Columbus, OH, 43210, USA.
  • Satoskar M; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • Satoskar S; Northeast Ohio Medical University, Rootstown, Ohio, 44272, USA.
  • Dagur PK; Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Silver Spring, MD, 20993, USA.
  • McCoy JP; Northeast Ohio Medical University, Rootstown, Ohio, 44272, USA.
  • Kamhawi S; National Institute of Heart, Lung and Blood Institute, NIH, Bethesda, MD, 20852, USA.
  • Valenzuela JG; National Institute of Heart, Lung and Blood Institute, NIH, Bethesda, MD, 20852, USA.
  • Hamano S; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Satoskar AR; Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
  • Matlashewski G; Department of Parasitology, Institute of Tropical Medicine (NEKKEN), The Joint Usage/Research Center on Tropical Disease, Nagasaki University, Nagasaki, Japan and Nagasaki University Graduate School of Biomedical Sciences Doctoral Leadership Program, Nagasaki, Japan.
  • Nakhasi HL; Department of Pathology and Microbiology, Ohio State University, Columbus, OH, 43210, USA. Abhay.Satoskar@osumc.edu.
Nat Commun ; 11(1): 3461, 2020 07 10.
Article en En | MEDLINE | ID: mdl-32651371
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Atenuadas / Leishmania major / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Atenuadas / Leishmania major / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Canadá