Clinical characteristics, outcomes and prognosticators in adult patients hospitalized with COVID-19.
Am J Infect Control
; 49(2): 158-165, 2021 02.
Article
en En
| MEDLINE
| ID: mdl-32652252
ABSTRACT
BACKGROUND:
COVID-19 is a novel disease caused by SARS-CoV-2.METHODS:
We conducted a retrospective evaluation of patients admitted with COVID-19 to one site in March 2020. Patients were stratified into 3 groups survivors who did not receive mechanical ventilation (MV), survivors who received MV, and those who received MV and died during hospitalization.RESULTS:
There were 140 hospitalizations; 22 deaths (mortality rate 15.7%), 83 (59%) survived and did not receive MV, 35 (25%) received MV and survived; 18 (12.9%) received MV and died. Thee mean age of each group was 57.8, 55.8 and 72.7 years, respectively (Pâ¯=â¯.0001). Of those who received MV and died, 61% were male (P = .01). More than half the patients (nâ¯=â¯90, 64%) were African American. First measured d-dimer >575.5 ng/mL, procalcitonin > 0.24 ng/mL, lactate dehydrogenase >445.6 units/L, and brain natriuretic peptide (BNP) >104.75 pg/mL had odds ratios of 10.5, 5, 4.5 and 2.9, respectively for MV (P < .05 for all). Peak BNP >167.5 pg/mL had an odds ratio of 6.7 for inpatient mortality when mechanically ventilated (P = .02).CONCLUSIONS:
Age and gender may impact outcomes in COVID-19. D-dimer, procalcitonin, lactate dehydrogenase and BNP may serve as early indicators of disease trajectory.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Respiración Artificial
/
SARS-CoV-2
/
COVID-19
/
Hospitalización
Tipo de estudio:
Etiology_studies
/
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am J Infect Control
Año:
2021
Tipo del documento:
Article
País de afiliación:
India