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Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.
Mahmoodi, Bakhtawar K; Tragante, Vinicius; Kleber, Marcus E; Holmes, Michael V; Schmidt, Amand F; McCubrey, Raymond O; Howe, Laurence J; Direk, Kenan; Allayee, Hooman; Baranova, Ekaterina V; Braund, Peter S; Delgado, Graciela E; Eriksson, Niclas; Gijsberts, Crystel M; Gong, Yan; Hartiala, Jaana; Heydarpour, Mahyar; Pasterkamp, Gerard; Kotti, Salma; Kuukasjärvi, Pekka; Lenzini, Petra A; Levin, Daniel; Lyytikäinen, Leo-Pekka; Muehlschlegel, Jochen D; Nelson, Christopher P; Nikus, Kjell; Pilbrow, Anna P; Wilson Tang, W H; van der Laan, Sander W; van Setten, Jessica; Vilmundarson, Ragnar O; Deanfield, John; Deloukas, Panos; Dudbridge, Frank; James, Stefan; Mordi, Ify R; Teren, Andrej; Bergmeijer, Thomas O; Body, Simon C; Bots, Michiel; Burkhardt, Ralph; Cooper-DeHoff, Rhonda M; Cresci, Sharon; Danchin, Nicolas; Doughty, Robert N; Grobbee, Diederick E; Hagström, Emil; Hazen, Stanley L; Held, Claes; Hoefer, Imo E.
Afiliación
  • Mahmoodi BK; St. Antonius Hospital, Department of Cardiology, Nieuwegein, the Netherlands (B.K.M., T.O.B., J.M.t.B.).
  • Tragante V; Division of Hemostasis and Thrombosis, Department of Hematology, UMC Groningen, University of Groningen, The Netherlands (B.K.M.).
  • Kleber ME; Department of Cardiology, Division Heart and Lungs (V.T., A.F.S., J.v.S., A.O.K., F.W.A.), UMC Utrecht, Utrecht University, the Netherlands.
  • Holmes MV; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (M.E.K., G.E.D., W.M.).
  • Schmidt AF; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health and Medical Research Council Population Health Research Unit, University of Oxford, United Kingdom (M.V.H.).
  • McCubrey RO; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital, United Kingdom (M.V.H.).
  • Howe LJ; Department of Cardiology, Division Heart and Lungs (V.T., A.F.S., J.v.S., A.O.K., F.W.A.), UMC Utrecht, Utrecht University, the Netherlands.
  • Direk K; Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, United Kingdom (A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A., R.S.P.).
  • Allayee H; Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (R.O.McC.).
  • Baranova EV; Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, United Kingdom (A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A., R.S.P.).
  • Braund PS; Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, United Kingdom (A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A., R.S.P.).
  • Delgado GE; Departments of Preventive Medicine and Biochemistry and Molecular Medicine (H.A., J.H.), Keck School of Medicine of University of Southern California, Los Angeles.
  • Eriksson N; Division of Pharmacoepidemiology and Clinical Pharmacology (E.V.B., O.H.K., A.H.M.-v.d.Z.), UMC Utrecht, Utrecht University, the Netherlands.
  • Gijsberts CM; Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, United Kingdom (P.S.B., C.P.N., N.J.S.).
  • Gong Y; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, United Kingdom (P.S.B., C.P.N., N.J.S.).
  • Hartiala J; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Germany (M.E.K., G.E.D., W.M.).
  • Heydarpour M; Uppsala Clinical Research Center, Sweden (N.E., S.J., C.H., A.Å., L.W.).
  • Pasterkamp G; Laboratory of Experimental Cardiology (C.M.G.), UMC Utrecht, Utrecht University, the Netherlands.
  • Kotti S; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (Y.G., R.M.C.-D.H., J.A.J.), University of Florida, Gainesville.
  • Kuukasjärvi P; Departments of Preventive Medicine and Biochemistry and Molecular Medicine (H.A., J.H.), Keck School of Medicine of University of Southern California, Los Angeles.
  • Lenzini PA; Institute for Genetic Medicine (J.H.), Keck School of Medicine of University of Southern California, Los Angeles.
  • Levin D; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA (M.H., J.D.M.).
  • Lyytikäinen LP; Harvard Medical School, Harvard University, Boston, MA (M.H., J.D.M.).
  • Muehlschlegel JD; Department of Clinical Chemistry (G.Pasterkamp), UMC Utrecht, Utrecht University, the Netherlands.
  • Nelson CP; Assistance Publique-Hôpitaux de Paris (APHP), Department of Clinical Pharmacology, Platform of Clinical Research of East Paris (URCEST-CRCEST-CRB HUEP-UPMC), France (S.K.).
  • Nikus K; Departments of Cardio-Thoracic Surgery (P.K., J.O.L.), Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Techonology, Tampere University, Finland.
  • Pilbrow AP; Department of Genetics, Statistical Genomics Division (P.A.L., S.C.), Washington University School of Medicine, Saint Louis, MO.
  • Wilson Tang WH; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Scotland, United Kingdom (D.L., I.R.M., C.C.L.).
  • van der Laan SW; Clinical Chemistry (L.-P.L., T.L.), Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Techonology, Tampere University, Finland.
  • van Setten J; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland (L.-P.L., T.L.).
  • Vilmundarson RO; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA (M.H., J.D.M.).
  • Deanfield J; Harvard Medical School, Harvard University, Boston, MA (M.H., J.D.M.).
  • Deloukas P; Laboratory of Experimental Cardiology (C.M.G.), UMC Utrecht, Utrecht University, the Netherlands.
  • Dudbridge F; Department of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, United Kingdom (P.S.B., C.P.N., N.J.S.).
  • James S; Cardiology (K.N.), Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Techonology, Tampere University, Finland.
  • Mordi IR; Department of Cardiology (K.N.), Heart Center, Tampere University Hospital, Finland.
  • Teren A; The Christchurch Heart Institute, University of Otago Christchurch, New Zealand (A.P.P., A.M.R., V.A.C.).
  • Bergmeijer TO; Department of Cardiovascular and Metabolic Sciences, Lerner Research institute (W.H.W.T., S.L.H.), Cleveland Clinic, OH.
  • Body SC; Department of Cardiovascular Medicine, Heart and Vascular Institute (W.H.W.T.), Cleveland Clinic, OH.
  • Bots M; Central Diagnostics Laboratory, Division Laboratories, Pharmacy, and Biomedical Genetics (S.W.v.d.L.), UMC Utrecht, Utrecht University, the Netherlands.
  • Burkhardt R; Department of Cardiology, Division Heart and Lungs (V.T., A.F.S., J.v.S., A.O.K., F.W.A.), UMC Utrecht, Utrecht University, the Netherlands.
  • Cooper-DeHoff RM; Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ontario, Canada (R.O.V., A.F.R.S.).
  • Cresci S; Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, United Kingdom (A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A., R.S.P.).
  • Danchin N; William Harvey Research Institute, Barts and the London Medical School, and the Centre for Genomic Health, Queen Mary University of London, United Kingdom (P.D.).
  • Doughty RN; Department of Health Sciences, University of Leicester, United Kingdom (F.D.).
  • Grobbee DE; Uppsala Clinical Research Center, Sweden (N.E., S.J., C.H., A.Å., L.W.).
  • Hagström E; Department of Medical Sciences, Cardiology, Uppsala University, Sweden (S.J., E.H., C.H., A.Å., L.W.).
  • Hazen SL; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Scotland, United Kingdom (D.L., I.R.M., C.C.L.).
  • Held C; Heart Center Leipzig, Germany (A.T.).
  • Hoefer IE; LIFE Research Center for Civilization Diseases (A.T., R.B., M.Scholz, J.T.), University of Leipzig, Germany.
Circulation ; 142(6): 546-555, 2020 08 11.
Article en En | MEDLINE | ID: mdl-32654539
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trombosis / Factor V / Enfermedad Coronaria / Genotipo Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Circulation Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trombosis / Factor V / Enfermedad Coronaria / Genotipo Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Circulation Año: 2020 Tipo del documento: Article