The staphylococcal biofilm protein Aap forms a tetrameric species as a necessary intermediate before amyloidogenesis.

Yarawsky, Alexander E; Herr, Andrew B

Yarawsky, Alexander E; Herr, Andrew B.

Afiliación

Yarawsky AE; Graduate Program in Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Herr AB; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. Electronic address: Andrew.Herr@cchmc.org.

J Biol Chem ; 295(37): 12840-12850, 2020 09 11.

Article en En | MEDLINE | ID: mdl-32665400

Asunto(s)

Amiloide; Proteínas Bacterianas; Biopelículas; Multimerización de Proteína; Staphylococcus epidermidis/fisiología; Zinc; Amiloide/química; Amiloide/metabolismo; Proteínas Bacterianas/química; Proteínas Bacterianas/metabolismo; Secuencias Repetitivas de Aminoácido; Staphylococcus epidermidis/química; Zinc/química; Zinc/metabolismo

Palabras clave

analytical ultracentrifugation; biofilm; biophysics; chemical modification; oligomerization; protein aggregation; protein chemical modification; sedimentation equilibrium; thermodynamics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Staphylococcus epidermidis / Proteínas Bacterianas / Zinc / Biopelículas / Multimerización de Proteína / Amiloide Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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