The Periostin/Integrin-&#945;v Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver.

Biswas, Atreyi; Roy, Irene M; Babu, Prathibha C; Manesia, Javed; Schouteden, Sarah; Vijayakurup, Vinod; Anto, Ruby John; Huelsken, Joerg; Lacy-Hulbert, Adam; Verfaillie, Catherine M; Khurana, Satish

The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver.

Biswas, Atreyi; Roy, Irene M; Babu, Prathibha C; Manesia, Javed; Schouteden, Sarah; Vijayakurup, Vinod; Anto, Ruby John; Huelsken, Joerg; Lacy-Hulbert, Adam; Verfaillie, Catherine M; Khurana, Satish.

Afiliación

Biswas A; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram, Kerala 695551, India.
Roy IM; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram, Kerala 695551, India.
Babu PC; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram, Kerala 695551, India.
Manesia J; Inter-Departmental Stem Cell Institute, KU Leuven, 3000 Leuven, Belgium.
Schouteden S; Inter-Departmental Stem Cell Institute, KU Leuven, 3000 Leuven, Belgium.
Vijayakurup V; Rajiv Gandhi Centre for Biotechnology, Poojappura, Thiruvananthapuram, Kerala, India.
Anto RJ; Rajiv Gandhi Centre for Biotechnology, Poojappura, Thiruvananthapuram, Kerala, India.
Huelsken J; École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Lacy-Hulbert A; Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.
Verfaillie CM; Inter-Departmental Stem Cell Institute, KU Leuven, 3000 Leuven, Belgium.
Khurana S; School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram, Kerala 695551, India. Electronic address: satishkhurana@iisertvm.ac.in.

Stem Cell Reports ; 15(2): 340-357, 2020 08 11.

Article en En | MEDLINE | ID: mdl-32735820

Asunto(s)

Moléculas de Adhesión Celular/metabolismo; Feto/citología; Células Madre Hematopoyéticas/metabolismo; Integrina alfaV/metabolismo; Hígado/embriología; Transducción de Señal; Animales; Daño del ADN; Reparación del ADN; Endotelio Vascular/metabolismo; Eliminación de Gen; Integrina beta3/metabolismo; Ratones; Ratones Noqueados; Fenotipo

Palabras clave

DNA damage responses; POSTN-ITGAV interaction; fetal liver; fetal liver niche; hematopoietic stem cells; outside-in integrin signaling

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Transducción de Señal / Moléculas de Adhesión Celular / Integrina alfaV / Feto / Hígado Límite: Animals Idioma: En Revista: Stem Cell Reports Año: 2020 Tipo del documento: Article País de afiliación: India

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