Enhanced efficacy of endonuclease inhibitor baloxavir acid against orthobunyaviruses when used in combination with ribavirin.

Ter Horst, Sebastiaan; Fernandez-Garcia, Yaiza; Bassetto, Marcella; Günther, Stephan; Brancale, Andrea; Neyts, Johan; Rocha-Pereira, Joana

Ter Horst, Sebastiaan; Fernandez-Garcia, Yaiza; Bassetto, Marcella; Günther, Stephan; Brancale, Andrea; Neyts, Johan; Rocha-Pereira, Joana.

Afiliación

Ter Horst S; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Fernandez-Garcia Y; Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.
Bassetto M; Department of Chemistry, College of Science, Swansea University, Swansea, UK.
Günther S; Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.
Brancale A; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.
Neyts J; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Rocha-Pereira J; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.

J Antimicrob Chemother ; 75(11): 3189-3193, 2020 11 01.

Article en En | MEDLINE | ID: mdl-32766680

Asunto(s)

Orthobunyavirus; Ribavirina; Antivirales/farmacología; Dibenzotiepinas; Endonucleasas; Humanos; Morfolinas; Piridonas; Ribavirina/farmacología; Triazinas

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ribavirina / Orthobunyavirus Límite: Humans Idioma: En Revista: J Antimicrob Chemother Año: 2020 Tipo del documento: Article País de afiliación: Bélgica

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