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Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic.
Chin, Emily N; Yu, Chenguang; Vartabedian, Vincent F; Jia, Ying; Kumar, Manoj; Gamo, Ana M; Vernier, William; Ali, Sabrina H; Kissai, Mildred; Lazar, Daniel C; Nguyen, Nhan; Pereira, Laura E; Benish, Brent; Woods, Ashley K; Joseph, Sean B; Chu, Alan; Johnson, Kristen A; Sander, Philipp N; Martínez-Peña, Francisco; Hampton, Eric N; Young, Travis S; Wolan, Dennis W; Chatterjee, Arnab K; Schultz, Peter G; Petrassi, H Michael; Teijaro, John R; Lairson, Luke L.
Afiliación
  • Chin EN; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Yu C; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Vartabedian VF; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Jia Y; Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Kumar M; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Gamo AM; Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Vernier W; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Ali SH; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Kissai M; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Lazar DC; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Nguyen N; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Pereira LE; Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Benish B; Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Woods AK; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Joseph SB; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Chu A; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Johnson KA; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Sander PN; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Martínez-Peña F; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Hampton EN; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Young TS; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Wolan DW; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Chatterjee AK; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Schultz PG; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Petrassi HM; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Teijaro JR; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Lairson LL; California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, CA 92037, USA.
Science ; 369(6506): 993-999, 2020 Aug 21.
Article en En | MEDLINE | ID: mdl-32820126
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Materiales Biomiméticos / Proteínas de la Membrana / Antineoplásicos / Nucleótidos Cíclicos Límite: Animals / Humans Idioma: En Revista: Science Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Materiales Biomiméticos / Proteínas de la Membrana / Antineoplásicos / Nucleótidos Cíclicos Límite: Animals / Humans Idioma: En Revista: Science Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos