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A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
de Vries, Maren; Mohamed, Adil S; Prescott, Rachel A; Valero-Jimenez, Ana M; Desvignes, Ludovic; O'Connor, Rebecca; Steppan, Claire; Devlin, Joseph C; Ivanova, Ellie; Herrera, Alberto; Schinlever, Austin; Loose, Paige; Ruggles, Kelly; Koralov, Sergei B; Anderson, Annaliesa S; Binder, Joseph; Dittmann, Meike.
Afiliación
  • de Vries M; Department of Microbiology, New York University Grossman School of Medicine, New York 10016, USA.
  • Mohamed AS; Department of Microbiology, New York University Grossman School of Medicine, New York 10016, USA.
  • Prescott RA; Department of Microbiology, New York University Grossman School of Medicine, New York 10016, USA.
  • Valero-Jimenez AM; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York 10016, USA.
  • Desvignes L; Department of Microbiology, New York University Grossman School of Medicine, New York 10016, USA.
  • O'Connor R; Department of Medicine, New York University Grossman School of Medicine, New York 10016, USA.
  • Steppan C; Office of Science & Research, NYU Langone Health, New York 10016, USA.
  • Devlin JC; Pfizer Discovery Sciences, Groton, CT 06340, USA.
  • Ivanova E; Pfizer Discovery Sciences, Groton, CT 06340, USA.
  • Herrera A; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York 10016, USA.
  • Schinlever A; Institute of Systems Genetics, New York University Grossman School of Medicine, New York 10016, USA.
  • Loose P; Department of Pathology, New York University Grossman School of Medicine, New York 10016, USA.
  • Ruggles K; Department of Pathology, New York University Grossman School of Medicine, New York 10016, USA.
  • Koralov SB; Department of Microbiology, New York University Grossman School of Medicine, New York 10016, USA.
  • Anderson AS; Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York 10016, USA.
  • Binder J; Department of Microbiology, New York University Grossman School of Medicine, New York 10016, USA.
  • Dittmann M; Institute of Systems Genetics, New York University Grossman School of Medicine, New York 10016, USA.
bioRxiv ; 2021 Feb 19.
Article en En | MEDLINE | ID: mdl-32869028

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos