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Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos.
Naert, Thomas; Tulkens, Dieter; Edwards, Nicole A; Carron, Marjolein; Shaidani, Nikko-Ideen; Wlizla, Marcin; Boel, Annekatrien; Demuynck, Suzan; Horb, Marko E; Coucke, Paul; Willaert, Andy; Zorn, Aaron M; Vleminckx, Kris.
Afiliación
  • Naert T; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 71, 9052, Ghent (Zwijnaarde), Belgium.
  • Tulkens D; Cancer Research Institute Ghent, Ghent, Belgium.
  • Edwards NA; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 71, 9052, Ghent (Zwijnaarde), Belgium.
  • Carron M; Cancer Research Institute Ghent, Ghent, Belgium.
  • Shaidani NI; Division of Developmental Biology, Perinatal Institute, and Center for Stem Cell and Organoid Medicine (CuSTOM), Cincinnati Children's Hospital, Cincinnati, USA.
  • Wlizla M; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 71, 9052, Ghent (Zwijnaarde), Belgium.
  • Boel A; Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Demuynck S; National Xenopus Resource and Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA, 02543, USA.
  • Horb ME; National Xenopus Resource and Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA, 02543, USA.
  • Coucke P; Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Willaert A; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 71, 9052, Ghent (Zwijnaarde), Belgium.
  • Zorn AM; Cancer Research Institute Ghent, Ghent, Belgium.
  • Vleminckx K; National Xenopus Resource and Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA, 02543, USA.
Sci Rep ; 10(1): 14662, 2020 09 04.
Article en En | MEDLINE | ID: mdl-32887910
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Xenopus laevis / Pez Cebra / Penetrancia / Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Xenopus laevis / Pez Cebra / Penetrancia / Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Bélgica