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Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity.
Song, Runzhe; Wang, Yue; Wang, Minghui; Gao, Ruixuan; Yang, Teng; Yang, Song; Yang, Cai-Guang; Jin, Yongsheng; Zou, Siyuan; Cai, Jianfeng; Fan, Renhua; He, Qiuqin.
Afiliación
  • Song R; Department of Chemistry, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai 200438, China.
  • Wang Y; Department of Chemistry, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai 200438, China.
  • Wang M; Department of Chemistry, University of South Florida, Tampa, FL 33620, United States.
  • Gao R; Department of Chemistry, University of South Florida, Tampa, FL 33620, United States.
  • Yang T; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China; State Key Laboratory of Drug Research, Sha
  • Yang S; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals, Guizhou University, Guiyang 550025, China.
  • Yang CG; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Jin Y; School of Pharmacy, The Second Military Medical University, Shanghai 200433, China.
  • Zou S; Department of Chemistry, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai 200438, China.
  • Cai J; Department of Chemistry, University of South Florida, Tampa, FL 33620, United States. Electronic address: jianfengcai@usf.edu.
  • Fan R; Department of Chemistry, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai 200438, China. Electronic address: rhfan@fudan.edu.cn.
  • He Q; Department of Chemistry, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai 200438, China. Electronic address: qqhe@fudan.edu.cn.
Bioorg Chem ; 103: 104176, 2020 10.
Article en En | MEDLINE | ID: mdl-32891858
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Fluoroquinolonas Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Fluoroquinolonas Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article País de afiliación: China