The Protective Effects of 18<i>ß</i>-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling.

Chen, Haiming; Liu, Huazhen; Tang, Bin; Chen, Yuchao; Han, Ling; Yu, Jingjie; Yan, Yuhong; Lu, Chuanjian

The Protective Effects of 18ß-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling.

Chen, Haiming; Liu, Huazhen; Tang, Bin; Chen, Yuchao; Han, Ling; Yu, Jingjie; Yan, Yuhong; Lu, Chuanjian.

Afiliación

Chen H; State Key laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510115, China.
Liu H; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou 510115, China.
Tang B; State Key laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510115, China.
Chen Y; State Key laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510115, China.
Han L; State Key laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510115, China.
Yu J; State Key laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510115, China.
Yan Y; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou 510115, China.
Lu C; State Key laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510115, China.

J Immunol Res ; 2020: 1980456, 2020.

Article en En | MEDLINE | ID: mdl-32908937

Asunto(s)

Ácido Glicirretínico/análogos & derivados; Imiquimod/efectos adversos; Psoriasis/etiología; Psoriasis/metabolismo; Factor de Transcripción STAT3/metabolismo; Transducción de Señal/efectos de los fármacos; Serina-Treonina Quinasas TOR/metabolismo; Animales; Antiinflamatorios/química; Antiinflamatorios/farmacología; Citocinas/genética; Citocinas/metabolismo; Modelos Animales de Enfermedad; Ácido Glicirretínico/química; Ácido Glicirretínico/farmacología; Inmunohistoquímica; Mediadores de Inflamación/metabolismo; Ratones; Sustancias Protectoras/química; Sustancias Protectoras/farmacología; Psoriasis/diagnóstico; Psoriasis/tratamiento farmacológico; Subgrupos de Linfocitos T/efectos de los fármacos; Subgrupos de Linfocitos T/inmunología; Subgrupos de Linfocitos T/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Psoriasis / Transducción de Señal / Factor de Transcripción STAT3 / Serina-Treonina Quinasas TOR / Imiquimod / Ácido Glicirretínico Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Immunol Res Año: 2020 Tipo del documento: Article País de afiliación: China

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