Impact of the beta-lacta test on the management of urinary tract infections at the emergency department.
Infect Dis (Lond)
; 53(1): 52-60, 2021 Jan.
Article
en En
| MEDLINE
| ID: mdl-32960659
ABSTRACT
INTRODUCTION:
Rapid detection of extended-spectrum ß-lactamases is essential. In this study, we evaluated the potential impact of ß-lacta test on both the times to appropriate antibiotic therapy and to the implementation of patient isolation measures. PATIENTS ANDMETHODS:
We included prospectively all the patients admitted to the emergency department for clinical suspicion of urinary tract infection. Compared with physician's decision, we analysed the potential impact of ß-lacta test on the initial antibiotic therapy and on the implementation of hygiene measures. This study has been registered under number NCT02897609.RESULTS:
We included 203 patients, 43% with acute pyelonephritis and 21% with acute prostatitis. The ß-lacta test had a 95.2% sensitivity and a 99.5% specificity to detect extended-spectrum ß-lactamases. Taking the ß-lacta test results into account would have decreased significantly both the times to appropriate therapy and to isolation measures from 54 to 2.7 h and from 55.2 to 2.6 h, respectively.CONCLUSION:
The ß-lacta test could reduce significantly the times to appropriate therapy and implementation of isolations measures.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones Urinarias
/
Beta-Lactamasas
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
/
Male
Idioma:
En
Revista:
Infect Dis (Lond)
Año:
2021
Tipo del documento:
Article
País de afiliación:
Francia