Characterization of essential domains in HSD17B13 for cellular localization and enzymatic activity.

Ma, Yanling; Karki, Suman; Brown, Philip M; Lin, Dennis D; Podszun, Maren C; Zhou, Wenchang; Belyaeva, Olga V; Kedishvili, Natalia Y; Rotman, Yaron

Ma, Yanling; Karki, Suman; Brown, Philip M; Lin, Dennis D; Podszun, Maren C; Zhou, Wenchang; Belyaeva, Olga V; Kedishvili, Natalia Y; Rotman, Yaron.

Afiliación

Ma Y; Liver and Energy Metabolism Section, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Karki S; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Brown PM; Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama, Birmingham, Birmingham, AL, USA.
Lin DD; Liver and Energy Metabolism Section, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Podszun MC; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Zhou W; Liver and Energy Metabolism Section, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Belyaeva OV; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Kedishvili NY; Liver and Energy Metabolism Section, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.
Rotman Y; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, the National Institutes of Health, Bethesda, MD, USA.

J Lipid Res ; 61(11): 1400-1409, 2020 11.

Article en En | MEDLINE | ID: mdl-32973038

Asunto(s)

17-Hidroxiesteroide Deshidrogenasas/metabolismo; Hepatopatías/tratamiento farmacológico; 17-Hidroxiesteroide Deshidrogenasas/análisis; 17-Hidroxiesteroide Deshidrogenasas/antagonistas & inhibidores; Células Cultivadas; Enfermedad Crónica; Humanos; Hepatopatías/metabolismo; Hepatopatías/patología; Bibliotecas de Moléculas Pequeñas/farmacología

Palabras clave

alcoholic liver disease; enzyme regulation; lipid droplets; nonalcoholic fatty liver disease; protein structure; retinoids

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: 17-Hidroxiesteroide Deshidrogenasas / Hepatopatías Límite: Humans Idioma: En Revista: J Lipid Res Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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