Experimental study on sleep quality affected by carbon dioxide concentration.

This study comprehensively investigated the impact of indoor carbon dioxide (CO2 ) concentration on sleep quality. Three experimental conditions (800, 1900, 3000 ppm) were created in chambers decorated as bedroom and other environmental parameters that may influence the sleep quality were under strict control. Sleep quality of 12 subjects (6 men and 6 women) was monitored for 54 consecutive days through sleep quality questionnaire and physiological measures. Both subjective and physiological results showed that sleep quality decreased significantly with the increase of CO2 concentration, and the comprehensive questionnaire score at 3000 ppm was only 80.8% of that at 800 ppm. A linear positive correlation was found between sleep onset latency (SOL) and CO2 concentration, while a linear negative correlation occurred between slow-wave sleep (SWS) and CO2 concentration. In addition, in the same sleep environment, men had higher subjective questionnaire scores after wake-up, longer SWS and shorter SOL, which lead to a better sleep quality compared with women, and there was a significant gender difference in sleep quality at 800 ppm (P < .05).