Silencing Celsr2 inhibits the proliferation and migration of Schwann cells through suppressing the Wnt/ß-catenin signaling pathway.

Zhou, Xiang; Zhan, Zhaoying; Tang, Chaogang; Li, Jiachun; Zheng, Xiaoju; Zhu, Shuang; Qi, Jian

Zhou, Xiang; Zhan, Zhaoying; Tang, Chaogang; Li, Jiachun; Zheng, Xiaoju; Zhu, Shuang; Qi, Jian.

Afiliación

Zhou X; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China. Electronic address: zhoux87@mail.sysu.edu.cn.
Zhan Z; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Tang C; Department of Cerebrovascular Disease, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, China.
Li J; Department of Orthopedic, The Seventh Affiliated Hospital of Sun Yat-sen University, 628# Zhenyuan Road, Shenzhen, Guangdong, 518100, China.
Zheng X; Department of Hand and Podiatric Microsurgery, Xian Fengcheng Hospital, Xian, 710021, China.
Zhu S; Department of joint and orthopedic, orthopedic center, Zhujiang Hospital of Southern Medical University, Guangzhou, 510280, China. Electronic address: zsddn.2008@163.com.
Qi J; Department of Microsurgery, Trauma and Hand Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China. Electronic address: qijian@mail.sysu.edu.cn.

Biochem Biophys Res Commun ; 533(4): 623-630, 2020 12 17.

Article en En | MEDLINE | ID: mdl-32988580

Asunto(s)

Cadherinas/metabolismo; Movimiento Celular/genética; Proliferación Celular/genética; Receptores Acoplados a Proteínas G/metabolismo; Células de Schwann/metabolismo; Neuropatía Ciática/metabolismo; Animales; Cadherinas/genética; Núcleo Celular/metabolismo; Células Cultivadas; Silenciador del Gen; Glucógeno Sintasa Quinasa 3 beta/antagonistas & inhibidores; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Antígeno Ki-67/metabolismo; Masculino; Nervios Periféricos/metabolismo; Fosforilación; ARN Interferente Pequeño; Ratas; Ratas Sprague-Dawley; Receptores Acoplados a Proteínas G/genética; Neuropatía Ciática/genética; Vía de Señalización Wnt/genética; beta Catenina/metabolismo

Palabras clave

Celsr2; GSK3ß; Schwann cells; Wnt/ ß-catenin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células de Schwann / Cadherinas / Movimiento Celular / Neuropatía Ciática / Receptores Acoplados a Proteínas G / Proliferación Celular Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2020 Tipo del documento: Article

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