Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation.

Xin, Jingxue; Zhang, Hui; He, Yaoxi; Duren, Zhana; Bai, Caijuan; Chen, Lang; Luo, Xin; Yan, Dong-Sheng; Zhang, Chaoyu; Zhu, Xiang; Yuan, Qiuyue; Feng, Zhanying; Cui, Chaoying; Qi, Xuebin; Wong, Wing Hung; Wang, Yong; Su, Bing

Xin, Jingxue; Zhang, Hui; He, Yaoxi; Duren, Zhana; Bai, Caijuan; Chen, Lang; Luo, Xin; Yan, Dong-Sheng; Zhang, Chaoyu; Zhu, Xiang; Yuan, Qiuyue; Feng, Zhanying; Cui, Chaoying; Qi, Xuebin; Wong, Wing Hung; Wang, Yong; Su, Bing.

Afiliación

Xin J; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China.
Zhang H; CEMS, NCMIS, MDIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, 100190, Beijing, China.
He Y; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, 650223, Kunming, China.
Duren Z; Bio-X Program, Stanford University, Stanford, CA, 94305, USA.
Bai C; University of Chinese Academy of Sciences, 100101, Beijing, China.
Chen L; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China.
Luo X; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, 650223, Kunming, China.
Yan DS; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China.
Zhang C; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, 650223, Kunming, China.
Zhu X; University of Chinese Academy of Sciences, 100101, Beijing, China.
Yuan Q; Departments of Statistics, Stanford University, Stanford, CA, 94305, USA.
Feng Z; Center for Human Genetics and Department of Genetics and Biochemistry, Clemson University, Greenwood, SC, 29646, USA.
Cui C; High Altitude Medical Research Center, School of Medicine, Tibetan University, 850000, Lhasa, China.
Qi X; CEMS, NCMIS, MDIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, 100190, Beijing, China.
Ouzhuluobu; University of Chinese Academy of Sciences, 100101, Beijing, China.
Wong WH; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China.
Wang Y; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, 650223, Kunming, China.
Su B; University of Chinese Academy of Sciences, 100101, Beijing, China.

Nat Commun ; 11(1): 4928, 2020 10 01.

Article en En | MEDLINE | ID: mdl-33004791

Asunto(s)

Aclimatación/genética; Cromatina/metabolismo; Etnicidad/genética; Redes Reguladoras de Genes; Modelos Genéticos; Altitud; Mal de Altura/etnología; Mal de Altura/genética; Mal de Altura/metabolismo; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/genética; Hipoxia de la Célula/genética; Células Cultivadas; Cromatina/genética; Secuenciación de Inmunoprecipitación de Cromatina; Resistencia a la Enfermedad/genética; Femenino; Regulación de la Expresión Génica; Células Endoteliales de la Vena Umbilical Humana; Humanos; Hipoxia/genética; Hipoxia/metabolismo; Oxígeno/metabolismo; Polimorfismo de Nucleótido Simple; Embarazo; Cultivo Primario de Células; RNA-Seq; Elementos Reguladores de la Transcripción/genética; Selección Genética; Tibet/etnología; Factores de Transcripción/metabolismo; Secuenciación Completa del Genoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cromatina / Etnicidad / Redes Reguladoras de Genes / Aclimatación / Modelos Genéticos Tipo de estudio: Prognostic_studies Límite: Female / Humans / Pregnancy País/Región como asunto: Asia Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: China

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