Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis.

Pirino, Breanne E; Spodnick, Mary B; Gargiulo, Andrew T; Curtis, Genevieve R; Barson, Jessica R; Karkhanis, Anushree N

Pirino, Breanne E; Spodnick, Mary B; Gargiulo, Andrew T; Curtis, Genevieve R; Barson, Jessica R; Karkhanis, Anushree N.

Afiliación

Pirino BE; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA. Electronic address: bep46@drexel.edu.
Spodnick MB; Binghamton University - SUNY, Department of Psychology, Binghamton, NY, 13902, USA. Electronic address: mspodni1@binghamton.edu.
Gargiulo AT; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA. Electronic address: agargiulo1@brynmawr.edu.
Curtis GR; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA. Electronic address: grc37@drexel.edu.
Barson JR; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA. Electronic address: jrb455@drexel.edu.
Karkhanis AN; Binghamton University - SUNY, Department of Psychology, Binghamton, NY, 13902, USA. Electronic address: akarkhan@binghamton.edu.

Neuropharmacology ; 181: 108341, 2020 12 15.

Article en En | MEDLINE | ID: mdl-33011200

Asunto(s)

Ansiedad/psicología; Conducta Animal/efectos de los fármacos; Dopamina/metabolismo; Núcleo Accumbens/efectos de los fármacos; Receptores Opioides kappa/efectos de los fármacos; 3,4-Dicloro-N-metil-N-(2-(1-pirrolidinil)-ciclohexil)-bencenacetamida, (trans)-Isómero/farmacología; Afecto; Animales; Reacción de Prevención/efectos de los fármacos; Encéfalo/patología; Dinorfinas/metabolismo; Conducta Exploratoria/efectos de los fármacos; Femenino; Masculino; Actividad Motora/efectos de los fármacos; Ratas; Ratas Long-Evans; Recompensa

Palabras clave

Avoidance behavior; Dopamine; Kappa opioid receptors; Nucleus accumbens shell; Rostro-caudal; U50,488

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ansiedad / Conducta Animal / Dopamina / Receptores Opioides kappa / Núcleo Accumbens Límite: Animals Idioma: En Revista: Neuropharmacology Año: 2020 Tipo del documento: Article

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