The peptidyl prolyl isomerase, PIN1 induces angiogenesis through direct interaction with HIF-2&#945;.

Choi, Min-A; Saeidi, Soma; Han, Hyeong-Jun; Kim, Su-Jung; Kwon, Nayoung; Kim, Do-Hee; Min, Sang-Hyun; Choi, Bu Young; Surh, Young-Joon

The peptidyl prolyl isomerase, PIN1 induces angiogenesis through direct interaction with HIF-2α.

Choi, Min-A; Saeidi, Soma; Han, Hyeong-Jun; Kim, Su-Jung; Kwon, Nayoung; Kim, Do-Hee; Min, Sang-Hyun; Choi, Bu Young; Surh, Young-Joon.

Afiliación

Choi MA; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Saeidi S; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Han HJ; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Kim SJ; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Kwon N; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Kim DH; Department of Chemistry, College of Convergence and Integrated Science, Kyonggi University, Suwon, Gyeonggi-do, 16227, South Korea.
Min SH; New Drug Development Center, Daegu Gyeongbuk Medical Innovation Foundation, Daegu, 701-310, South Korea.
Choi BY; Department of Pharmaceutical Science and Engineering, School of Convergence Bioscience and Technology, Seowon University, Chungbuk, 28674, South Korea.
Surh YJ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea; Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea;

Biochem Biophys Res Commun ; 533(4): 995-1003, 2020 12 17.

Article en En | MEDLINE | ID: mdl-33012513

Asunto(s)

Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/metabolismo; Peptidilprolil Isomerasa de Interacción con NIMA/metabolismo; Neovascularización Patológica/etiología; Animales; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/química; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico/genética; Embrión de Pollo; Femenino; Células HCT116; Células HEK293; Células Endoteliales de la Vena Umbilical Humana; Humanos; Masculino; Ratones; Células 3T3 NIH; Peptidilprolil Isomerasa de Interacción con NIMA/química; Peptidilprolil Isomerasa de Interacción con NIMA/genética; Neovascularización Patológica/genética; Neovascularización Patológica/metabolismo; Dominios y Motivos de Interacción de Proteínas; Estabilidad Proteica; Interferencia de ARN; ARN Interferente Pequeño/genética; Hipoxia Tumoral; Factor A de Crecimiento Endotelial Vascular/metabolismo

Palabras clave

Angiogenesis; HIF-2α; Hypoxia; PIN1; Peptidyl prolyl isomerase; VEGF

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Peptidilprolil Isomerasa de Interacción con NIMA / Neovascularización Patológica Límite: Animals / Female / Humans / Male Idioma: En Revista: Biochem Biophys Res Commun Año: 2020 Tipo del documento: Article País de afiliación: Corea del Sur

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