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Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo.
Wu, Qihui; Shaikh, Muhammad A; Meymand, Emily S; Zhang, Bin; Luk, Kelvin C; Trojanowski, John Q; Lee, Virginia M-Y.
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  • Wu Q; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA.
  • Shaikh MA; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA.
  • Meymand ES; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA.
  • Zhang B; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA.
  • Luk KC; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA.
  • Trojanowski JQ; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA.
  • Lee VM; Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104-4283, USA. vmylee@upenn.edu.
Acta Neuropathol ; 140(6): 831-849, 2020 12.
Article en En | MEDLINE | ID: mdl-33021680
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Alfa-Sinucleína / Sinucleinopatías / Degeneración Nerviosa / Neuronas Límite: Animals / Humans Idioma: En Revista: Acta Neuropathol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Alfa-Sinucleína / Sinucleinopatías / Degeneración Nerviosa / Neuronas Límite: Animals / Humans Idioma: En Revista: Acta Neuropathol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos