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A soft and stretchable bilayer electrode array with independent functional layers for the next generation of brain machine interfaces.
Graudejus, Oliver; Barton, Cody; Ponce Wong, Ruben D; Rowan, Cami C; Oswalt, Denise; Greger, Bradley.
Afiliación
  • Graudejus O; School of Molecular Science, Arizona State University, Tempe, AZ, United States of America.
  • Barton C; BMSEED, Phoenix, AZ, United States of America.
  • Ponce Wong RD; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States of America.
  • Rowan CC; BMSEED, Phoenix, AZ, United States of America.
  • Oswalt D; BMSEED, Phoenix, AZ, United States of America.
  • Greger B; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States of America.
J Neural Eng ; 17(5): 056023, 2020 10 14.
Article en En | MEDLINE | ID: mdl-33052886
OBJECTIVE: Brain-Machine Interfaces (BMIs) hold great promises for advancing neuroprosthetics, robotics, and for providing treatment options for severe neurological diseases. The objective of this work is the development and in vivo evaluation of electrodes for BMIs that meet the needs to record brain activity at sub-millimeter resolution over a large area of the cortex while being soft and electromechanically robust (i.e. stretchable). APPROACH: Current electrodes require a trade-off between high spatiotemporal resolution and cortical coverage area. To address the needs for simultaneous high resolution and large cortical coverage, the prototype electrode array developed in this study employs a novel bilayer routing of soft and stretchable lead wires from the recording sites on the surface of the brain (electrocorticography, ECoG) to the data acquisition system. MAIN RESULTS: To validate the recording characteristics, the array was implanted in healthy felines for up to 5 months. Neural signals recorded from both layers of the device showed elevated mid-frequency structures typical of local field potential (LFP) signals that were stable in amplitude over implant duration, and also exhibited consistent frequency-dependent modulation after anesthesia induction by Telazol. SIGNIFICANCE: The successful development of a soft and stretchable large-area, high resolution micro ECoG electrode array (lahrµECoG) is an important step to meet the neurotechnological needs of advanced BMI applications.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Interfaces Cerebro-Computador Límite: Animals Idioma: En Revista: J Neural Eng Asunto de la revista: NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Interfaces Cerebro-Computador Límite: Animals Idioma: En Revista: J Neural Eng Asunto de la revista: NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos