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Discovery of First-In-Class Potent and Selective Tropomyosin Receptor Kinase Degraders.
Chen, Liqun; Chen, Yanke; Zhang, Chunyan; Jiao, Bingyang; Liang, Sheng; Tan, Qiong; Chai, Hongyu; Yu, Weihua; Qian, Yongzheng; Yang, Hui; Yao, Wuyi; Yu, Jianguo; Luo, Ying; Plewe, Michael; Wang, Jialiang; Han, Xiao-Ran; Liu, Jing.
Afiliación
  • Chen L; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Chen Y; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Zhang C; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Jiao B; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Liang S; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Tan Q; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Chai H; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Yu W; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Qian Y; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Yang H; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Yao W; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Yu J; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Luo Y; Cullgen Inc., 12671 High Bluff Drive Suite 130, San Diego, California 92130, United States.
  • Plewe M; Cullgen Inc., 12671 High Bluff Drive Suite 130, San Diego, California 92130, United States.
  • Wang J; Cullgen Inc., 12671 High Bluff Drive Suite 130, San Diego, California 92130, United States.
  • Han XR; Cullgen (Shanghai), Inc., 230 ChuanHong Road, Building 6, Chuansha, Pudong New Area, Shanghai 201202, People's Republic of China.
  • Liu J; Cullgen Inc., 12671 High Bluff Drive Suite 130, San Diego, California 92130, United States.
J Med Chem ; 63(23): 14562-14575, 2020 12 10.
Article en En | MEDLINE | ID: mdl-33058680
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridazinas / Talidomida / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridazinas / Talidomida / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article