Pineal teratoma with nephroblastic component in a newborn male: Case report and review of the literature.
J Clin Neurosci
; 80: 207-214, 2020 Oct.
Article
en En
| MEDLINE
| ID: mdl-33099347
ABSTRACT
Neonatal germ cell tumors are rare and comprise both benign and malignant neoplasms. Teratoma with nephroblastoma is a malignant subset defined pathologically by the presence of nephroblastoma and teratoma elements. Although teratoma with nephroblastoma is most often found in the kidney, 24 of 59 reported cases are associated with extrarenal locations, such as the mediastinum or retroperitoneum. To our knowledge, this is the first patient in the literature with intracranial/pineal teratoma with nephroblastoma, which was managed with staged transcranial approaches resulting in gross total resection and no adjuvant therapy (surveillance observation imaging). We further augmented the patient's management by comprehensive genomic profiling of the tumor to better understand the molecular biology and explore options for targeted therapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Pinealoma
/
Teratoma
/
Neoplasias Complejas y Mixtas
/
Tumor de Wilms
Límite:
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
J Clin Neurosci
Asunto de la revista:
NEUROLOGIA
Año:
2020
Tipo del documento:
Article