Acute liver failure is regulated by MYC- and microbiome-dependent programs.

Kolodziejczyk, Aleksandra A; Federici, Sara; Zmora, Niv; Mohapatra, Gayatree; Dori-Bachash, Mally; Hornstein, Shanni; Leshem, Avner; Reuveni, Debby; Zigmond, Ehud; Tobar, Ana; Salame, Tomer Meir; Harmelin, Alon; Shlomai, Amir; Shapiro, Hagit; Amit, Ido; Elinav, Eran

Kolodziejczyk, Aleksandra A; Federici, Sara; Zmora, Niv; Mohapatra, Gayatree; Dori-Bachash, Mally; Hornstein, Shanni; Leshem, Avner; Reuveni, Debby; Zigmond, Ehud; Tobar, Ana; Salame, Tomer Meir; Harmelin, Alon; Shlomai, Amir; Shapiro, Hagit; Amit, Ido; Elinav, Eran.

Afiliación

Kolodziejczyk AA; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Federici S; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Zmora N; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Mohapatra G; The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Dori-Bachash M; The Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Hornstein S; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Leshem A; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Reuveni D; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Zigmond E; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Tobar A; Department of Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Salame TM; The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Harmelin A; The Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Shlomai A; The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Shapiro H; The Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Amit I; The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Elinav E; Department of Pathology, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.

Nat Med ; 26(12): 1899-1911, 2020 12.

Article en En | MEDLINE | ID: mdl-33106666

Asunto(s)

Fallo Hepático Agudo/genética; Microbiota/genética; Proteínas Proto-Oncogénicas c-myc/genética; Transcriptoma/efectos de los fármacos; Acetaminofén/toxicidad; Animales; Células Estrelladas Hepáticas/efectos de los fármacos; Células Estrelladas Hepáticas/metabolismo; Humanos; Macrófagos del Hígado/efectos de los fármacos; Macrófagos del Hígado/metabolismo; Hígado/efectos de los fármacos; Hígado/metabolismo; Hígado/patología; Fallo Hepático Agudo/inducido químicamente; Fallo Hepático Agudo/patología; Trasplante de Hígado/efectos adversos; Ratones; Microbiota/efectos de los fármacos; Neutrófilos/efectos de los fármacos; Neutrófilos/metabolismo; Análisis de la Célula Individual; Tioacetamida/toxicidad; Receptores Toll-Like/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-myc / Fallo Hepático Agudo / Transcriptoma / Microbiota Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Israel

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