Gonadotroph tumours with a low SF-1 labelling index are more likely to recur and are associated with enrichment of the PI3K-AKT pathway.

Hickman, Richard A; Bruce, Jeffrey N; Otten, Marc; Khandji, Alexander G; Flowers, Xena E; Siegelin, Markus; Lopes, Beatriz; Faust, Phyllis L; Freda, Pamela U

Hickman, Richard A; Bruce, Jeffrey N; Otten, Marc; Khandji, Alexander G; Flowers, Xena E; Siegelin, Markus; Lopes, Beatriz; Faust, Phyllis L; Freda, Pamela U.

Afiliación

Hickman RA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Bruce JN; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
Otten M; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.
Khandji AG; Department of Radiology, Columbia University Medical Center, New York, NY, USA.
Flowers XE; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Siegelin M; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Lopes B; Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA, USA.
Faust PL; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
Freda PU; Department of Medicine, Columbia University Medical Center, New York, NY, USA.

Neuropathol Appl Neurobiol ; 47(3): 415-427, 2021 04.

Article en En | MEDLINE | ID: mdl-33128255

Asunto(s)

Biomarcadores de Tumor/metabolismo; Recurrencia Local de Neoplasia/patología; Tumores Neuroendocrinos/patología; Neoplasias Hipofisarias/patología; Factor Esteroidogénico 1/metabolismo; Adulto; Anciano; Estudios de Cohortes; Femenino; Humanos; Masculino; Persona de Mediana Edad; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Transducción de Señal/fisiología

Palabras clave

RNA-seq; gene set enrichment analysis; gonadotroph tumour; steroidogenic factor-1

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Hipofisarias / Biomarcadores de Tumor / Tumores Neuroendocrinos / Factor Esteroidogénico 1 / Recurrencia Local de Neoplasia Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neuropathol Appl Neurobiol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google